Nuclear factor I
{{Short description|Family of transcription factors}}
Nuclear factor I (NF-I) is a family of closely related transcription factors. They constitutively bind as dimers to specific sequences of DNA with high affinity.{{cite journal |vauthors=Blomquist P, Belikov S, Wrange O |title=Increased nuclear factor 1 binding to its nucleosomal site mediated by sequence-dependent DNA structure |journal=Nucleic Acids Res. |volume=27 |issue=2 |pages=517–25 |date=January 1999 |pmid=9862974 |pmc=148209 |doi= 10.1093/nar/27.2.517}} Family members contain an unusual DNA binding domain that binds to the recognition sequence 5'-TTGGCXXXXXGCCAA-3'.{{cite book |author=Walter F. Boron |title=Medical Physiology: A Cellular And Molecular Approaoch |publisher=Elsevier/Saunders |year=2003 |pages=125–126 |isbn=1-4160-2328-3 }}
Subtypes include: