Nucleoside-specific porin

{{Pfam_box

| Symbol = Channel_Tsx

| Name = Nucleoside-specific channel-forming protein, Tsx

| image =1tly_opm.png

| width =220

| caption =

| Pfam= PF03502

| InterPro= IPR003055

| SMART=

| Prosite =

| SCOP =

| TCDB = 1.B.10

| OPM family= 9

| OPM protein= 1tly

| PDB=

}}

Nucleoside-specific porin (the tsx gene of Escherichia coli) is an outer membrane protein, Tsx, which constitutes the receptor for colicin K and Bacteriophage T6, and functions as a substrate-specific channel for nucleosides and deoxy-nucleosides.

name="PUB00006257">{{cite journal |vauthors=Bremer E, Martinussen J, Middendorf A, Valentin-Hansen P |title=Analysis of the tsx gene, which encodes a nucleoside-specific channel-forming protein (Tsx) in the outer membrane of Escherichia coli |journal=Gene |volume=96 |issue=1 |pages=59–65 |year=1990 |pmid=2265760 |doi=10.1016/0378-1119(90)90341-N|s2cid=7488190 }} The protein contains 294 amino acids, the first 22 of which are characteristic of a bacterial signal sequence peptide. Tsx shows no significant similarities to general bacterial porins.