OR11H7
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Olfactory receptor family 11 subfamily H member 7 (gene/pseudogene) is a protein that in humans is encoded by the OR11H7 gene.
{{cite web
| title = Entrez Gene: Olfactory receptor family 11 subfamily H member 7 (gene/pseudogene)
| url = http://www.ncbi.nlm.nih.gov/gene/390441
| access-date = 2020-04-13
}}
Function
In most humans, OR11H7 is a pseudogene, meaning it does not result in the creation of a functional olfactory receptor protein that binds to specific odorants. Some individuals, however, carry a single-nucleotide polymorphism on one or both chromosomes which transforms it from a pseudogene into an intact gene, and they are significantly more likely to exhibit hyperosmia to the chemical isovaleric acid. Isovaleric acid was shown to be a ligand of OR11H7.{{cite journal | vauthors = Menashe I, Abaffy T, Hasin Y, Goshen S, Yahalom V, Luetje CW, Lancet D | title = Genetic elucidation of human hyperosmia to isovaleric acid | journal = PLOS Biology | volume = 5 | issue = 11 | pages = e284 | date = October 2007 | pmid = 17973576 | pmc = 2043052 | doi = 10.1371/journal.pbio.0050284 | doi-access = free }}