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OR1D5

{{short description|Protein-coding gene in humans}}

{{Infobox_gene}}

Olfactory receptor 1D5 is a protein that in humans is encoded by the OR1D5 gene.{{cite journal | vauthors = Glusman G, Sosinsky A, Ben-Asher E, Avidan N, Sonkin D, Bahar A, Rosenthal A, Clifton S, Roe B, Ferraz C, Demaille J, Lancet D | title = Sequence, structure, and evolution of a complete human olfactory receptor gene cluster | journal = Genomics | volume = 63 | issue = 2 | pages = 227–45 |date=Apr 2000 | pmid = 10673334 | doi = 10.1006/geno.1999.6030 | s2cid = 23416814 }}{{cite web | title = Entrez Gene: OR1D5 olfactory receptor, family 1, subfamily D, member 5| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8386}}

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Olfactory receptors]] interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

References

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Further reading

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  • {{cite journal | vauthors=Selbie LA, Townsend-Nicholson A, Iismaa TP, Shine J |title=Novel G protein-coupled receptors: a gene family of putative human olfactory receptor sequences. |journal=Brain Res. Mol. Brain Res. |volume=13 |issue= 1–2 |pages= 159–63 |year= 1992 |pmid= 1315913 |doi=10.1016/0169-328X(92)90057-I }}
  • {{cite journal |vauthors=Fuchs T, Malecova B, Linhart C, etal |title=DEFOG: a practical scheme for deciphering families of genes |journal=Genomics |volume=80 |issue= 3 |pages= 295–302 |year= 2003 |pmid= 12213199 |doi=10.1006/geno.2002.6830 |url=http://www.cs.tau.ac.il/~roded/defog.pdf }}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal | vauthors=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584–9 |year= 2004 |pmid= 14983052 |doi=10.1073/pnas.0307882100 | pmc=356993 |bibcode=2004PNAS..101.2584M |doi-access=free }}

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External links

  • {{MeshName|OR1D5+protein,+human}}

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{{Olfactory receptors}}

Category:Olfactory receptors

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