OR2K2

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{{Short description|Protein-coding gene in the species Homo sapiens}}

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Olfactory receptor 2K2 is a protein that in humans is encoded by the OR2K2 gene.{{cite journal | vauthors = Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J| title = Expression of members of the putative olfactory receptor gene family in mammalian germ cells | journal = Nature | volume = 355 | issue = 6359 | pages = 453–5 |date=Mar 1992 | pmid = 1370859 | doi = 10.1038/355453a0 | bibcode = 1992Natur.355..453P | s2cid = 43926 |display-authors=etal}}{{cite journal | vauthors = Aloni R, Olender T, Lancet D | title = Ancient genomic architecture for mammalian olfactory receptor clusters | journal = Genome Biol | volume = 7 | issue = 10 | pages = R88 |date=Jan 2007 | pmid = 17010214 | pmc = 1794568 | doi = 10.1186/gb-2006-7-10-r88 | doi-access = free }}{{cite web | title = Entrez Gene: OR2K2 olfactory receptor, family 2, subfamily K, member 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26248}}

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.{{cite web | title = Entrez Gene: OR2K2 olfactory receptor, family 2, subfamily K, member 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26248}}

See also

References

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Further reading

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  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |doi-access=free |bibcode=2002PNAS...9916899M }}
  • {{cite journal | vauthors=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584–9 |year= 2004 |pmid= 14983052 |doi=10.1073/pnas.0307882100 | pmc=356993 |bibcode=2004PNAS..101.2584M |doi-access=free }}
  • {{cite journal |vauthors=Humphray SJ, Oliver K, Hunt AR, etal |title=DNA sequence and analysis of human chromosome 9. |journal=Nature |volume=429 |issue= 6990 |pages= 369–74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465 | pmc=2734081 |bibcode=2004Natur.429..369H }}
  • {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}

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