OR2M4
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Olfactory receptor 2M4 is a protein that in humans is encoded by the OR2M4 gene.{{cite journal | vauthors = Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J| title = Expression of members of the putative olfactory receptor gene family in mammalian germ cells | journal = Nature | volume = 355 | issue = 6359 | pages = 453–5 |date=Mar 1992 | pmid = 1370859 | doi = 10.1038/355453a0 | bibcode = 1992Natur.355..453P | s2cid = 43926 |display-authors=etal}}{{cite journal | vauthors = Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M | title = Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species | journal = Genomics | volume = 39 | issue = 3 | pages = 239–46 |date=Apr 1997 | pmid = 9119360 | doi = 10.1006/geno.1996.4490 }}{{cite web | title = Entrez Gene: OR2M4 olfactory receptor, family 2, subfamily M, member 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26245}}
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.{{cite web | title = Entrez Gene: OR2M4 olfactory receptor, family 2, subfamily M, member 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26245}}
See also
References
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Further reading
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- {{cite journal |vauthors=Fuchs T, Malecova B, Linhart C, etal |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295–302 |year= 2003 |pmid= 12213199 |doi=10.1006/geno.2002.6830 |citeseerx=10.1.1.135.3652 }}
- {{cite journal | vauthors=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584–9 |year= 2004 |pmid= 14983052 |doi=10.1073/pnas.0307882100 | pmc=356993 |bibcode=2004PNAS..101.2584M |doi-access=free }}
- {{cite journal |vauthors=Gregory SG, Barlow KF, McLay KE, etal |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 |bibcode=2006Natur.441..315G |doi-access= free }}
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External links
- {{MeshName|OR2M4+protein,+human}}
{{NLM content}}
{{Olfactory receptors}}
{{transmembranereceptor-stub}}