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OR3A2

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Olfactory receptor 3A2 is a protein that in humans is encoded by the OR3A2 gene.{{cite journal | vauthors = Glusman G, Clifton S, Roe B, Lancet D | title = Sequence analysis in the olfactory receptor gene cluster on human chromosome 17: recombinatorial events affecting receptor diversity | journal = Genomics | volume = 37 | issue = 2 | pages = 147–60 |date=Feb 1997 | pmid = 8921386 | doi = 10.1006/geno.1996.0536 }}{{cite journal | vauthors = Glusman G, Sosinsky A, Ben-Asher E, Avidan N, Sonkin D, Bahar A, Rosenthal A, Clifton S, Roe B, Ferraz C, Demaille J, Lancet D | title = Sequence, structure, and evolution of a complete human olfactory receptor gene cluster | journal = Genomics | volume = 63 | issue = 2 | pages = 227–45 |date=Apr 2000 | pmid = 10673334 | doi = 10.1006/geno.1999.6030 | s2cid = 23416814 }}{{cite web | title = Entrez Gene: OR3A2 olfactory receptor, family 3, subfamily A, member 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4995}}

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

References

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Further reading

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  • {{cite journal |vauthors=Ben-Arie N, Lancet D, Taylor C, etal |title=Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire. |journal=Hum. Mol. Genet. |volume=3 |issue= 2 |pages= 229–35 |year= 1994 |pmid= 8004088 |doi=10.1093/hmg/3.2.229 }}
  • {{cite journal |vauthors=Rouquier S, Taviaux S, Trask BJ, etal |title=Distribution of olfactory receptor genes in the human genome. |journal=Nat. Genet. |volume=18 |issue= 3 |pages= 243–50 |year= 1998 |pmid= 9500546 |doi= 10.1038/ng0398-243 |s2cid=31129045 }}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal | vauthors=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584–9 |year= 2004 |pmid= 14983052 |doi=10.1073/pnas.0307882100 | pmc=356993 |bibcode=2004PNAS..101.2584M |doi-access=free }}

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External links

  • {{MeshName|OR3A2+protein,+human}}

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{{Olfactory receptors}}

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Category:Olfactory receptors