OR4K1

{{Short description|Protein-coding gene in the species Homo sapiens}}

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Olfactory receptor 4K1 is a protein that in humans is encoded by the OR4K1 gene.{{cite web | title = Entrez Gene: OR4K1 olfactory receptor, family 4, subfamily K, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79544}}

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

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Further reading

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  • {{cite journal | author=Fuchs T |title=DEFOG: a practical scheme for deciphering families of genes |journal=Genomics |volume=80 |issue= 3 |pages= 295–302 |year= 2003 |pmid= 12213199 |doi=10.1006/geno.2002.6830 |name-list-style=vanc| author2=Malecova B | author3=Linhart C | display-authors=3 | last4=Sharan | first4=Roded | last5=Khen | first5=Miriam | last6=Herwig | first6=Ralf | last7=Shmulevich | first7=Dmitry | last8=Elkon | first8=Rani | last9=Steinfath | first9=Matthias }}
  • {{cite journal |vauthors=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584–9 |year= 2004 |pmid= 14983052 |doi=10.1073/pnas.0307882100 | pmc=356993 |bibcode=2004PNAS..101.2584M |doi-access=free }}

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{{Olfactory receptors}}

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Category:Olfactory receptors