OR52A1

{{Short description|Protein-coding gene in humans}}

{{Infobox_gene}}

Olfactory receptor 52A1 is a protein that in humans is encoded by the OR52A1 gene.{{cite journal | vauthors = Feingold EA, Penny LA, Nienhuis AW, Forget BG | title = An olfactory receptor gene is located in the extended human beta-globin gene cluster and is expressed in erythroid cells | journal = Genomics | volume = 61 | issue = 1 | pages = 15–23 |date=Nov 1999 | pmid = 10512676 | doi = 10.1006/geno.1999.5935 | doi-access = free }}{{cite web | title = Entrez Gene: OR52A1 olfactory receptor, family 52, subfamily A, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23538}}

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.{{cite web | title = Entrez Gene: OR52A1 olfactory receptor, family 52, subfamily A, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23538}}

See also

References

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Further reading

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  • {{cite journal |vauthors=Bulger M, Bender MA, van Doorninck JH, etal |title=Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 26 |pages= 14560–5 |year= 2001 |pmid= 11121057 |doi= 10.1073/pnas.97.26.14560 | pmc=18958 |doi-access=free |bibcode=2000PNAS...9714560B }}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal | vauthors=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584–9 |year= 2004 |pmid= 14983052 |doi=10.1073/pnas.0307882100 | pmc=356993 |bibcode=2004PNAS..101.2584M |doi-access=free }}
  • {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}

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