OR7A5
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Olfactory receptor 7A5 is a protein that in humans is encoded by the OR7A5 gene.{{cite web | title = Entrez Gene: OR7A5 olfactory receptor, family 7, subfamily A, member 5| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26659}}
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
See also
References
{{reflist}}
Further reading
{{refbegin | 2}}
- {{cite journal | author=Gerhard DS |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–2127 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-style=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}
- {{cite journal | author=Grimwood J |title=The DNA sequence and biology of human chromosome 19 |journal=Nature |volume=428 |issue= 6982 |pages= 529–535 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399 |name-list-style=vanc| author2=Gordon LA | author3=Olsen A | display-authors=3 | last4=Terry | first4=Astrid | last5=Schmutz | first5=Jeremy | last6=Lamerdin | first6=Jane | last7=Hellsten | first7=Uffe | last8=Goodstein | first8=David | last9=Couronne | first9=Olivier |bibcode=2004Natur.428..529G | doi-access=free }}
- {{cite journal |vauthors=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584–2589 |year= 2004 |pmid= 14983052 |doi=10.1073/pnas.0307882100 | pmc=356993 |bibcode=2004PNAS..101.2584M |doi-access=free }}
- {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–16903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-style=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal | author=Fuchs T |title=DEFOG: a practical scheme for deciphering families of genes |journal=Genomics |volume=80 |issue= 3 |pages= 295–302 |year= 2003 |pmid= 12213199 |doi=10.1006/geno.2002.6830 |name-list-style=vanc| author2=Malecova B | author3=Linhart C | display-authors=3 | last4=Sharan | first4=Roded | last5=Khen | first5=Miriam | last6=Herwig | first6=Ralf | last7=Shmulevich | first7=Dmitry | last8=Elkon | first8=Rani | last9=Steinfath | first9=Matthias }}
- {{cite journal |vauthors=Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M |title=Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome |journal=Biochem. Biophys. Res. Commun. |volume=237 |issue= 2 |pages= 283–287 |year= 1997 |pmid= 9268701 |doi= 10.1006/bbrc.1997.7043 }}
- {{cite journal |vauthors=Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M |title=Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species |journal=Genomics |volume=39 |issue= 3 |pages= 239–246 |year= 1997 |pmid= 9119360 |doi= 10.1006/geno.1996.4490 }}
- {{cite journal | author=Parmentier M |title=Expression of members of the putative olfactory receptor gene family in mammalian germ cells |journal=Nature |volume=355 |issue= 6359 |pages= 453–455 |year= 1992 |pmid= 1370859 |doi= 10.1038/355453a0 |name-list-style=vanc| author2=Libert F | author3=Schurmans S | display-authors=3 | last4=Schiffmann | first4=Serge | last5=Lefort | first5=Anne | last6=Eggerickx | first6=Dominique | last7=Ledent | first7=Catherine | last8=Mollereau | first8=Catherine | last9=Gérard | first9=Catherine |bibcode=1992Natur.355..453P |s2cid=43926 }}
{{refend}}
External links
- {{MeshName|OR7A5+protein,+human}}
{{NLM content}}
{{Olfactory receptors}}
{{transmembranereceptor-stub}}