Oncocyte
{{Short description|Epithelial cell with excess mitochondria}}
File:Cytopathology of Warthin's tumor.jpg of Warthin's tumor, with typical cellular features (and a relatively uncommon binucleated cell).Image by Mikael Häggström, MD. References for entries:
- {{cite journal| author=Köybaşioğlu FF, Önal B, Han Ü, Adabağ A, Şahpaz A| title=Cytomorphological findings in diagnosis of Warthin tumor | journal=Turk J Med Sci | year= 2020 | volume= 50 | issue= 1 | pages= 148–154 | pmid=31769640 | doi=10.3906/sag-1901-215 | pmc=7080357 }}
Binucleation:
- {{cite web|url=http://repository-tnmgrmu.ac.in/464/1/200300307malliga.pdf|title=A correlative cytological and histopathological study on lesions of salivary gland|date=2006-10-18|author=Dr.S. Malliga}}
- Chan MKM, McGuire LJ: Cytodiagnosis of Lesions Presenting as Salivary Gland Swellings: A Report of Seven Cases. Diagn Cytopathol 8: 439-443, 1992b. Pap stain. The relatively large size of the oncocytes is seen when comparing to the lymphocyte.]]
File:Histopathology of apocrine metaplasia of breast, annotated.png showing apocrine-type metaplasia of the breast with typical oncocytes.Image by Mikael Häggström, MD. Reference for findings: {{cite web|url=https://www.pathologyoutlines.com/topic/breastapocrinemetaplasia.html|title=Apocrine metaplasia|author=Carlos C. Diez Freire, M.D., Shahla Masood, M.D.|website=Pathology Outlines}} Last author update: 28 May 2020. H&E stain.]]
Image:Renal_oncocytoma2.jpg. H&E stain.]]
An oncocyte is an epithelial cell characterized by an excessive number of mitochondria, resulting in an abundant acidophilic, granular cytoplasm. Oncocytes can be benign or malignant.
Other names
Also known as:
- Hürthle cell (thyroid gland only)
- Oxyphilic cell
- Askanazy cell
- Apocrine-type metaplasia (breast gland only).
- Oncocytic cell
Etymology
Derived from the Greek root onco-, which means mass, bulk.
See also
- Hurthle cell carcinoma, a variant of follicular thyroid carcinoma.
- Oncocytoma, a tumour composed of oncocytes, may be found as a less common salivary gland neoplasm also known as oxyphilic adenoma.
- Renal oncocytoma, a kidney tumour composed of oncocytes.
References
{{Reflist}}
External links
- [http://www.wordinfo.info/words/index/info/view_unit/1474 Wordinfo - words containing onco-, onocho-, -onchus]