Oncomodulin 2
{{Short description|Protein-coding gene in the species Homo sapiens}}
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Oncomodulin 2, also known as OCM2, is a human gene that is similar to oncomodulin.
Oncomodulin is a high-affinity calcium ion-binding protein. It belongs to the superfamily of calmodulin proteins, also known as the EF-hand proteins. Oncomodulin 2 is an oncodevelopmental protein found in early embryonic cells in the placenta and also in tumors.{{cite web | title = Entrez Gene: OCM oncomodulin| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4951}}
References
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Further reading
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- {{cite journal |vauthors=Pauls TL, Cox JA, Berchtold MW |title=The Ca2+(-)binding proteins parvalbumin and oncomodulin and their genes: new structural and functional findings. |journal=Biochim. Biophys. Acta |volume=1306 |issue= 1 |pages= 39–54 |year= 1996 |pmid= 8611623 |doi= 10.1016/0167-4781(95)00221-9}}
- {{cite journal |vauthors=Belkacemi L, Simoneau L, Lafond J |title=Calcium-binding proteins: distribution and implication in mammalian placenta. |journal=Endocrine |volume=19 |issue= 1 |pages= 57–64 |year= 2003 |pmid= 12583602 |doi=10.1385/ENDO:19:1:57 |s2cid=28802052 }}
- {{cite journal |vauthors=Ritzler JM, Sawhney R, Geurts van Kessel AH, etal |title=The genes for the highly homologous Ca(2+)-binding proteins oncomodulin and parvalbumin are not linked in the human genome. |journal=Genomics |volume=12 |issue= 3 |pages= 567–72 |year= 1992 |pmid= 1559707 |doi=10.1016/0888-7543(92)90449-3 }}
- {{cite journal |vauthors=Palmer EJ, MacManus JP, Mutus B |title=Inhibition of glutathione reductase by oncomodulin. |journal=Arch. Biochem. Biophys. |volume=277 |issue= 1 |pages= 149–54 |year= 1990 |pmid= 2306116 |doi=10.1016/0003-9861(90)90563-E }}
- {{cite journal |vauthors=Mutus B, Palmer EJ, MacManus JP |title=Disulfide-linked dimer of oncomodulin: comparison to calmodulin. |journal=Biochemistry |volume=27 |issue= 15 |pages= 5615–22 |year= 1988 |pmid= 3179268 |doi=10.1021/bi00415a033 }}
- {{cite journal |vauthors=Gillen MF, Banville D, Rutledge RG, etal |title=A complete complementary DNA for the oncodevelopmental calcium-binding protein, oncomodulin. |journal=J. Biol. Chem. |volume=262 |issue= 11 |pages= 5308–12 |year= 1987 |doi=10.1016/S0021-9258(18)61189-5 |pmid= 3558395 |doi-access=free }}
- {{cite journal |vauthors=MacManus JP, Brewer LM, Whitfield JF |title=The widely-distributed tumour protein, oncomodulin, is a normal constituent of human and rodent placentas. |journal=Cancer Lett. |volume=27 |issue= 2 |pages= 145–51 |year= 1985 |pmid= 4005827 |doi=10.1016/0304-3835(85)90103-X }}
- {{cite journal |vauthors=Blum JK, Berchtold MW |title=Calmodulin-like effect of oncomodulin on cell proliferation. |journal=J. Cell. Physiol. |volume=160 |issue= 3 |pages= 455–62 |year= 1994 |pmid= 8077283 |doi= 10.1002/jcp.1041600308 |s2cid=25079233 }}
- {{cite journal |vauthors=Föhr UG, Weber BR, Müntener M, etal |title=Human alpha and beta parvalbumins. Structure and tissue-specific expression. |journal=Eur. J. Biochem. |volume=215 |issue= 3 |pages= 719–27 |year= 1993 |pmid= 8354278 |doi=10.1111/j.1432-1033.1993.tb18084.x |doi-access=free }}
- {{cite journal |vauthors=Sakaguchi N, Henzl MT, Thalmann I, etal |title=Oncomodulin is expressed exclusively by outer hair cells in the organ of Corti. |journal=J. Histochem. Cytochem. |volume=46 |issue= 1 |pages= 29–40 |year= 2000 |pmid= 9405492 |doi= 10.1177/002215549804600105 |doi-access= free }}
- {{cite journal |title=Toward a complete human genome sequence. |journal=Genome Res. |volume=8 |issue= 11 |pages= 1097–108 |year= 1999 |pmid= 9847074 |doi= 10.1101/gr.8.11.1097|doi-access=free |last1=Sanger Centre |first1=The |last2=Washington University Genome Sequencing Cente |first2=The }}
- {{cite journal |vauthors=Harrington JJ, Sherf B, Rundlett S, etal |title=Creation of genome-wide protein expression libraries using random activation of gene expression. |journal=Nat. Biotechnol. |volume=19 |issue= 5 |pages= 440–5 |year= 2001 |pmid= 11329013 |doi= 10.1038/88107 |s2cid=25064683 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal |vauthors=Hillier LW, Fulton RS, Fulton LA, etal |title=The DNA sequence of human chromosome 7 |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782 |bibcode=2003Natur.424..157H |doi-access= free }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Babini E, Bertini I, Capozzi F, etal |title=Solution structure of human beta-parvalbumin and structural comparison with its paralog alpha-parvalbumin and with their rat orthologs |journal=Biochemistry |volume=43 |issue= 51 |pages= 16076–85 |year= 2005 |pmid= 15610002 |doi= 10.1021/bi048388o }}
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