Ortho-DOT
{{one source|date=November 2022}}
{{chembox
| verifiedrevid = 415883653
| ImageFile = Ortho-DOT.svg
| ImageSize =
| PIN = 1-[4,5-Dimethoxy-2-(methylsulfanyl)phenyl]propan-2-amine
| OtherNames = (±)-1-[4,5-dimethoxy-2-(methylsulfanyl)phenyl]propan-2-amine
|Section1={{Chembox Identifiers
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 127831
| InChI = 1/C12H19NO2S/c1-8(13)5-9-6-10(14-2)11(15-3)7-12(9)16-4/h6-8H,5,13H2,1-4H3
| InChIKey = GQUWSNDODZTHKC-UHFFFAOYAP
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 31077
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C12H19NO2S/c1-8(13)5-9-6-10(14-2)11(15-3)7-12(9)16-4/h6-8H,5,13H2,1-4H3
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = GQUWSNDODZTHKC-UHFFFAOYSA-N
| CASNo_Ref = {{cascite|correct|??}}
| CASNo = 79440-51-0
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = FQL7H4OV45
| PubChem = 144890
| SMILES = S(c1cc(OC)c(OC)cc1CC(N)C)C
}}
|Section2={{Chembox Properties
| Formula = C12H19NO2S
| MolarMass = 241.350 g/mol
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility = }}
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt = }}
}}
Ortho-DOT, or 4,5-dimethoxy-2-methylthioamphetamine, is a lesser-known psychedelic drug. Ortho-DOT was first synthesized by Alexander Shulgin. In his book PiHKAL (Phenethylamines i Have Known And Loved), neither the dosage nor the duration are known. Ortho-DOT produces few to no effects.[http://www.erowid.org/library/books_online/pihkal/pihkal139.shtml Ortho-DOT entry in PiHKAL] Very little data exists about the pharmacological properties, metabolism, and toxicity of Ortho-DOT.