Osama

• Osama (name), an Arabic given name
• Osama bin Laden (1957–2011), Saudi Arabia-born Islamist dissident and militant leader who founded al-Qaeda
• Ōsama (born 1960), Japanese musician

• Osama (film), a 2003 film made in Afghanistan
• Being Osama, a 2004 documentary film of six men named Osama

• "Osama" (song), a 2021 single by Zakes Bantwini
• Dinner With Osama, a 2008 collection of short stories by Marilyn Krysl
• Osama (novel), a 2011 World Fantasy Award-winning novel by Lavie Tidhar

• Ōsama Game, a Japanese 2011 horror film
• Osamu

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