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PARD3B

{{Short description|Protein-coding gene in the species Homo sapiens}}

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Partitioning defective 3 homolog B is a protein that in humans is encoded by the PARD3B gene.{{cite journal |vauthors=Hadano S, Hand CK, Osuga H, Yanagisawa Y, Otomo A, Devon RS, Miyamoto N, Showguchi-Miyata J, Okada Y, Singaraja R, Figlewicz DA, Kwiatkowski T, Hosler BA, Sagie T, Skaug J, Nasir J, Brown RH Jr, Scherer SW, Rouleau GA, Hayden MR, Ikeda JE | title = A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2 | journal = Nat Genet | volume = 29 | issue = 2 | pages = 166–73 |date=Oct 2001 | pmid = 11586298 | doi = 10.1038/ng1001-166 | s2cid = 52828189 }}{{cite journal |vauthors=Kohjima M, Noda Y, Takeya R, Saito N, Takeuchi K, Sumimoto H | title = PAR3beta, a novel homologue of the cell polarity protein PAR3, localizes to tight junctions | journal = Biochem Biophys Res Commun | volume = 299 | issue = 4 | pages = 641–6 |date=Dec 2002 | pmid = 12459187 | doi =10.1016/S0006-291X(02)02698-0 }}{{cite web | title = Entrez Gene: PARD3B par-3 partitioning defective 3 homolog B (C. elegans)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=117583}}

Interactions

PARD3B has been shown to interact with Mothers against decapentaplegic homolog 3.{{cite journal |last=Warner |first=Dennis R |author2=Pisano M Michele |author3=Roberts Emily A |author4=Greene Robert M |date=Mar 2003 |title=Identification of three novel Smad binding proteins involved in cell polarity |journal=FEBS Lett. |volume=539 |issue=1–3 |pages=167–73 |location = Netherlands| issn = 0014-5793| pmid = 12650946 |doi=10.1016/S0014-5793(03)00155-8 |s2cid=7429554 |doi-access=free }}

References

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Further reading

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  • {{cite journal |vauthors=Izaki T, Kamakura S, Kohjima M, Sumimoto H |title=Two forms of human Inscuteable-related protein that links Par3 to the Pins homologues LGN and AGS3 |journal=Biochem. Biophys. Res. Commun. |volume=341 |issue= 4 |pages= 1001–6 |year= 2006 |pmid= 16458856 |doi= 10.1016/j.bbrc.2006.01.050 }}
  • {{cite journal |vauthors=Benzinger A, Muster N, Koch HB, etal |title=Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer |journal=Mol. Cell. Proteomics |volume=4 |issue= 6 |pages= 785–95 |year= 2005 |pmid= 15778465 |doi= 10.1074/mcp.M500021-MCP200 |doi-access= free }}
  • {{cite journal |vauthors=Izaki T, Kamakura S, Kohjima M, Sumimoto H |title=Phosphorylation-dependent binding of 14-3-3 to Par3beta, a human Par3-related cell polarity protein |journal=Biochem. Biophys. Res. Commun. |volume=329 |issue= 1 |pages= 211–8 |year= 2005 |pmid= 15721295 |doi= 10.1016/j.bbrc.2005.01.115 }}
  • {{cite journal |vauthors=Jin J, Smith FD, Stark C, etal |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436–50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051 |s2cid=2371325 |doi-access=free |bibcode=2004CBio...14.1436J }}
  • {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |doi-access= free }}
  • {{cite journal |vauthors=Warner DR, Pisano MM, Roberts EA, Greene RM |title=Identification of three novel Smad binding proteins involved in cell polarity |journal=FEBS Lett. |volume=539 |issue= 1–3 |pages= 167–73 |year= 2003 |pmid= 12650946 |doi=10.1016/S0014-5793(03)00155-8 |s2cid=7429554 |doi-access=free }}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal |vauthors=Gao L, Macara IG, Joberty G |title=Multiple splice variants of Par3 and of a novel related gene, Par3L, produce proteins with different binding properties |journal=Gene |volume=294 |issue= 1–2 |pages= 99–107 |year= 2003 |pmid= 12234671 |doi=10.1016/S0378-1119(02)00681-9 }}

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