PARVB
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Beta-parvin is a protein that in humans is encoded by the PARVB gene.{{cite journal | vauthors = Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W | title = Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics | journal = Genome Res | volume = 10 | issue = 5 | pages = 703–13 |date=Aug 2000 | pmid = 10810093 | pmc = 310876 | doi =10.1101/gr.10.5.703 }}{{cite journal | vauthors = Olski TM, Noegel AA, Korenbaum E | title = Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily | journal = J Cell Sci | volume = 114 | issue = Pt 3 | pages = 525–38 |date=Feb 2001 | doi = 10.1242/jcs.114.3.525 | pmid = 11171322 }}{{cite web | title = Entrez Gene: PARVB parvin, beta| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29780}}
Members of the parvin family, including PARVB, PARVA and PARVG, are actin-binding proteins associated with focal contacts.[supplied by OMIM]{{cite web | title = Entrez Gene: PARVB parvin, beta| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29780}}
References
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Further reading
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- {{cite journal |vauthors=Dunham I, Shimizu N, Roe BA, etal |title=The DNA sequence of human chromosome 22. |journal=Nature |volume=402 |issue= 6761 |pages= 489–95 |year= 1999 |pmid= 10591208 |doi= 10.1038/990031 |bibcode=1999Natur.402..489D |doi-access= free }}
- {{cite journal |vauthors=Yamaji S, Suzuki A, Sugiyama Y, etal |title=A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction. |journal=J. Cell Biol. |volume=153 |issue= 6 |pages= 1251–64 |year= 2001 |pmid= 11402068 |doi=10.1083/jcb.153.6.1251 | pmc=2192033 }}
- {{cite journal | vauthors=Korenbaum E, Olski TM, Noegel AA |title=Genomic organization and expression profile of the parvin family of focal adhesion proteins in mice and humans. |journal=Gene |volume=279 |issue= 1 |pages= 69–79 |year= 2002 |pmid= 11722847 |doi=10.1016/S0378-1119(01)00743-0 }}
- {{cite journal |vauthors=Yamaji S, Suzuki A, Kanamori H, etal |title=Possible role of ILK-affixin complex in integrin-cytoskeleton linkage during platelet aggregation. |journal=Biochem. Biophys. Res. Commun. |volume=297 |issue= 5 |pages= 1324–31 |year= 2002 |pmid= 12372433 |doi=10.1016/S0006-291X(02)02381-1 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal | vauthors=Rosenberger G, Jantke I, Gal A, Kutsche K |title=Interaction of alphaPIX (ARHGEF6) with beta-parvin (PARVB) suggests an involvement of alphaPIX in integrin-mediated signaling. |journal=Hum. Mol. Genet. |volume=12 |issue= 2 |pages= 155–67 |year= 2003 |pmid= 12499396 |doi=10.1093/hmg/ddg019 |doi-access=free }}
- {{cite journal |vauthors=Collins JE, Goward ME, Cole CG, etal |title=Reevaluating human gene annotation: a second-generation analysis of chromosome 22. |journal=Genome Res. |volume=13 |issue= 1 |pages= 27–36 |year= 2003 |pmid= 12529303 |doi= 10.1101/gr.695703 | pmc=430954 }}
- {{cite journal |vauthors=Mishima W, Suzuki A, Yamaji S, etal |title=The first CH domain of affixin activates Cdc42 and Rac1 through alphaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor. |journal=Genes Cells |volume=9 |issue= 3 |pages= 193–204 |year= 2004 |pmid= 15005707 |doi=10.1111/j.1356-9597.2004.00717.x |doi-access=free }}
- {{cite journal |vauthors=Yamaji S, Suzuki A, Kanamori H, etal |title=Affixin interacts with alpha-actinin and mediates integrin signaling for reorganization of F-actin induced by initial cell-substrate interaction. |journal=J. Cell Biol. |volume=165 |issue= 4 |pages= 539–51 |year= 2004 |pmid= 15159419 |doi= 10.1083/jcb.200308141 | pmc=2172344 }}
- {{cite journal | vauthors=Zhang Y, Chen K, Tu Y, Wu C |title=Distinct roles of two structurally closely related focal adhesion proteins, alpha-parvins and beta-parvins, in regulation of cell morphology and survival. |journal=J. Biol. Chem. |volume=279 |issue= 40 |pages= 41695–705 |year= 2004 |pmid= 15284246 |doi= 10.1074/jbc.M401563200 |doi-access= free }}
- {{cite journal |vauthors=Mongroo PS, Johnstone CN, Naruszewicz I, etal |title=Beta-parvin inhibits integrin-linked kinase signaling and is downregulated in breast cancer. |journal=Oncogene |volume=23 |issue= 55 |pages= 8959–70 |year= 2004 |pmid= 15467740 |doi= 10.1038/sj.onc.1208112 |doi-access= free }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Matsuda C, Kameyama K, Tagawa K, etal |title=Dysferlin interacts with affixin (beta-parvin) at the sarcolemma. |journal=J. Neuropathol. Exp. Neurol. |volume=64 |issue= 4 |pages= 334–40 |year= 2005 |pmid= 15835269 |doi= 10.1093/jnen/64.4.334|doi-access=free }}
- {{cite journal |vauthors=Ewing RM, Chu P, Elisma F, etal |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= 1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 | pmc=1847948 }}
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