PDE1B
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B is an enzyme that in humans is encoded by the PDE1B gene.{{cite journal | vauthors = Jiang X, Li J, Paskind M, Epstein PM | title = Inhibition of calmodulin-dependent phosphodiesterase induces apoptosis in human leukemic cells | journal = Proc Natl Acad Sci U S A | volume = 93 | issue = 20 | pages = 11236–41 |date=Nov 1996 | pmid = 8855339 | pmc = 1074519 | doi =10.1073/pnas.93.20.11236 | bibcode = 1996PNAS...9311236J | doi-access = free }}{{cite journal | vauthors = Yu J, Wolda SL, Frazier AL, Florio VA, Martins TJ, Snyder PB, Harris EA, McCaw KN, Farrell CA, Steiner B, Bentley JK, Beavo JA, Ferguson K, Gelinas R | title = Identification and characterisation of a human calmodulin-stimulated phosphodiesterase PDE1B1 | journal = Cell Signal | volume = 9 | issue = 7 | pages = 519–29 |date=Feb 1998 | pmid = 9419816 | doi =10.1016/S0898-6568(97)00046-6 }}{{cite web | title = Entrez Gene: PDE1B phosphodiesterase 1B, calmodulin-dependent| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5153}}
References
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Further reading
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- {{cite journal |vauthors=Repaske DR, Swinnen JV, Jin SL, etal |title=A polymerase chain reaction strategy to identify and clone cyclic nucleotide phosphodiesterase cDNAs. Molecular cloning of the cDNA encoding the 63-kDa calmodulin-dependent phosphodiesterase |journal=J. Biol. Chem. |volume=267 |issue= 26 |pages= 18683–8 |year= 1992 |doi=10.1016/S0021-9258(19)37015-2 |pmid= 1326532 |doi-access=free }}
- {{cite journal |vauthors=Spence S, Rena G, Sullivan M, etal |title=Receptor-mediated stimulation of lipid signalling pathways in CHO cells elicits the rapid transient induction of the PDE1B isoform of Ca2+/calmodulin-stimulated cAMP phosphodiesterase |journal=Biochem. J. |volume=321 ( Pt 1) |issue= Pt 1|pages= 157–63 |year= 1997 |pmid= 9003415 |doi= 10.1042/bj3210157| pmc=1218050 }}
- {{cite journal |vauthors=Zauli G, Milani D, Mirandola P, etal |title=HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway |journal=FASEB J. |volume=15 |issue= 2 |pages= 483–91 |year= 2001 |pmid= 11156964 |doi= 10.1096/fj.00-0354com |doi-access=free |s2cid=26315564 }}
- {{cite journal | vauthors=Fidock M, Miller M, Lanfear J |title=Isolation and differential tissue distribution of two human cDNAs encoding PDE1 splice variants |journal=Cell. Signal. |volume=14 |issue= 1 |pages= 53–60 |year= 2002 |pmid= 11747989 |doi=10.1016/S0898-6568(01)00207-8 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal |vauthors=Ballif BA, Villén J, Beausoleil SA, etal |title=Phosphoproteomic analysis of the developing mouse brain |journal=Mol. Cell. Proteomics |volume=3 |issue= 11 |pages= 1093–101 |year= 2005 |pmid= 15345747 |doi= 10.1074/mcp.M400085-MCP200 |doi-access= free }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal | vauthors=Bender AT, Ostenson CL, Wang EH, Beavo JA |title=Selective up-regulation of PDE1B2 upon monocyte-to-macrophage differentiation |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 2 |pages= 497–502 |year= 2005 |pmid= 15625104 |doi= 10.1073/pnas.0408535102 | pmc=544304 |bibcode=2005PNAS..102..497B |doi-access=free }}
- {{cite journal | vauthors=Bender AT, Beavo JA |title=PDE1B2 regulates cGMP and a subset of the phenotypic characteristics acquired upon macrophage differentiation from a monocyte |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 2 |pages= 460–5 |year= 2006 |pmid= 16407168 |doi= 10.1073/pnas.0509972102 | pmc=1326187 |bibcode=2006PNAS..103..460B |doi-access=free }}
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{{PDB Gallery|geneid=5153}}
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