PDE2A
{{Short description|Protein-coding gene in the species Homo sapiens}}
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cGMP-dependent 3',5'-cyclic phosphodiesterase is an enzyme that in humans is encoded by the PDE2A gene.{{cite journal |vauthors=Rosman GJ, Martins TJ, Sonnenburg WK, Beavo JA, Ferguson K, Loughney K | title = Isolation and characterization of human cDNAs encoding a cGMP-stimulated 3',5'-cyclic nucleotide phosphodiesterase | journal = Gene | volume = 191 | issue = 1 | pages = 89–95 |date=Aug 1997 | pmid = 9210593 | doi =10.1016/S0378-1119(97)00046-2 }}{{cite web | title = Entrez Gene: PDE2A phosphodiesterase 2A, cGMP-stimulated| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5138}}
References
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Further reading
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- {{cite journal | author=Witzenrath M |title=Phosphodiesterase 2 inhibition diminished acute lung injury in murine pneumococcal pneumonia |journal=Critical Care Medicine |volume= 37|issue= 9 |pages= 584–590 |year= 2005 |pmid= 19114892 |doi= 10.1097/CCM.0b013e3181959814 | author2=Gutbier B | author3=Schmeck B | last4=Tenor | first4=Herrmann | last5=Seybold | first5=Joachim | last6=Kuelzer | first6=Raimund | last7=Grentzmann | first7=Guido | last8=Hatzelmann | first8=Armin | last9=Van Laak | first9=Vincent|s2cid=1060183 }}
- {{cite journal | author=Seybold J |title=Tumor necrosis factor-alpha-dependent expression of phosphodiesterase 2: role in endothelial hyperpermeability |journal=Blood |volume=105 |issue= 9 |pages= 3569–3576 |year= 2009 |pmid= 15650061 |doi= 10.1182/blood-2004-07-2729 | author2=Thomas D | author3=Witzenrath M | last4=Boral | first4=S | last5=Hocke | first5=AC | last6=Bürger | first6=A | last7=Hatzelmann | first7=A | last8=Tenor | first8=H | last9=Schudt | first9=C | doi-access=free }}
- {{cite journal | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–45 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 | author2=Suzuki Y | author3=Nishikawa T | last4=Otsuki | first4=Tetsuji | last5=Sugiyama | first5=Tomoyasu | last6=Irie | first6=Ryotaro | last7=Wakamatsu | first7=Ai | last8=Hayashi | first8=Koji | last9=Sato | first9=Hiroyuki
| doi-access=free }}
- {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–16903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 | author2=Feingold EA | author3=Grouse LH | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal | author=Martinez SE |title=The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 20 |pages= 13260–13265 |year= 2002 |pmid= 12271124 |doi= 10.1073/pnas.192374899 | pmc=130621 | author2=Wu AY | author3=Glavas NA | last4=Tang | first4=XB | last5=Turley | first5=S | last6=Hol | first6=WG | last7=Beavo | first7=JA |bibcode=2002PNAS...9913260M |doi-access=free }}
- {{cite journal |vauthors=Manns JM, Brenna KJ, Colman RW, Sheth SB |title=Differential regulation of human platelet responses by cGMP inhibited and stimulated cAMP phosphodiesterases |journal=Thromb. Haemost. |volume=87 |issue= 5 |pages= 873–9 |year= 2002 |pmid= 12038792 |doi= 10.1055/s-0037-1613099|s2cid=4637804 }}
- {{cite journal | author=Zauli G |title=HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway |journal=FASEB J. |volume=15 |issue= 2 |pages= 483–491 |year= 2001 |pmid= 11156964 |doi= 10.1096/fj.00-0354com | author2=Milani D | author3=Mirandola P | last4=Mazzoni | first4=M | last5=Secchiero | first5=P | last6=Miscia | first6=S | last7=Capitani | first7=S |doi-access=free |s2cid=26315564 }}
- {{cite journal |vauthors=Sadhu K, Hensley K, Florio VA, Wolda SL |title=Differential expression of the cyclic GMP-stimulated phosphodiesterase PDE2A in human venous and capillary endothelial cells |journal=J. Histochem. Cytochem. |volume=47 |issue= 7 |pages= 895–906 |year= 1999 |pmid= 10375378 |doi=10.1177/002215549904700707 |doi-access=free }}
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