PDE6

{{More medical citations needed|date=June 2021}}{{more science citations needed|date=June 2021}}Photoreceptor phosphodiesterase 6 (PDE6 or PDE-6) is a protein complex family, which is highly concentrated in the retina.{{cite journal | vauthors = Cote RH | title = Characteristics of photoreceptor PDE (PDE6): similarities and differences to PDE5 | journal = International Journal of Impotence Research | volume = 16 | pages = S28-33 | date = June 2004 | issue = Suppl 1 | pmid = 15224133 | doi = 10.1038/sj.ijir.3901212 | s2cid = 9220513 | doi-access = free }}{{cite journal | vauthors = Han J, Dinculescu A, Dai X, Du W, Smith WC, Pang J | title = Review: the history and role of naturally occurring mouse models with Pde6b mutations | journal = Molecular Vision | volume = 19 | pages = 2579–89 | date = December 2013 | pmid = 24367157 | pmc = 3869645 }}{{cite journal | vauthors = Cote RH | title = Photoreceptor phosphodiesterase (PDE6): activation and inactivation mechanisms during visual transduction in rods and cones | journal = Pflügers Archiv | date = April 2021 | volume = 473 | issue = 9 | pages = 1377–1391 | pmid = 33860373 | doi = 10.1007/s00424-021-02562-x | pmc=8376765 }}{{cite journal | vauthors = Azevedo MF, Faucz FR, Bimpaki E, Horvath A, Levy I, de Alexandre RB, Ahmad F, Manganiello V, Stratakis CA | display-authors = 6 | title = Clinical and molecular genetics of the phosphodiesterases (PDEs) | journal = Endocrine Reviews | volume = 35 | issue = 2 | pages = 195–233 | date = April 2014 | pmid = 24311737 | pmc = 3963262 | doi = 10.1210/er.2013-1053 }}