PFL

• Professional Fighters League, an American mixed martial arts league
• Peel Football League, an Australian rules football league
• Pioneer Football League, an NCAA Division I FCS football conference
• Professional Futsal League, an American sports league
• Philippines Football League, an association football league in the Philippines
• Polish Football League, an American football league in Poland

• First Professional Football League (Bulgaria)
• Professional Football League of Ukraine
• Russian Professional Football League
• TT Pro League, formerly the Professional Football League of Trinidad and Tobago
• Uzbekistan Super League

• Pyruvate formate lyase, an enzyme important in the regulation of anaerobic glucose metabolism
• Positive feedback loop

• PFL, ISO 639-3 language code for the Palatine German language
• People-first language

• Perth Freight Link, transport route for trucks to access Fremantle port starting at Muchea in Western Australia.
• Pacific Forum Line, a shipping alliance located in Nauru
• Partido da Frente Liberal (Liberal Front Party), a Brazilian political party
• Popular Front of Latvia, a former Latvian political party
• Priests for Life, an American-based Roman Catholic anti-abortion organization

• Paid Family Leave (California), a California law that extends unemployment disability compensation
• Pre-fader listen, a sound mixer function used for making a Fade (audio engineering)
• Purfleet railway station, Thurrock, Essex, England (National Rail station code PFL)

{{disambig}}