PHLDB1

{{Short description|Protein-coding gene in the species Homo sapiens}}

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Pleckstrin homology-like domain family B member 1 is a protein that in humans is encoded by the PHLDB1 gene.{{cite journal | vauthors = Katoh M, Katoh M | title = Identification and characterization of human LL5A gene and mouse Ll5a gene in silico | journal = Int J Oncol | volume = 23 | issue = 5 | pages = 1477–83 |date=Oct 2003 | pmid = 14532993 | doi = 10.3892/ijo.23.5.1477}}{{cite web | title = Entrez Gene: PHLDB1 pleckstrin homology-like domain, family B, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23187}}

The first PHLDB1 cDNA was cloned from a rat pituitary cDNA library and named as LL5 after the clone number.{{cite journal | vauthors = Levi L, Hanukoglu I, Raikhinstein M, Kohen F, Koch Y | title = Cloning of LL5, a novel protein encoding cDNA from a rat pituitary library. | journal = Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression | volume = 1216 | issue = 2 | pages = 342–4 | date = 16 November 1993 | pmid = 8241284 | doi=10.1016/0167-4781(93)90171-9 }}

References

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Further reading

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  • {{cite journal | vauthors = Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T | title = Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones | journal = DNA Res. | volume = 9 | issue = 3 | pages = 99–106 |date=June 2002 | pmid = 12168954 | doi = 10.1093/dnares/9.3.99 | doi-access = free }}
  • {{cite journal | vauthors = Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro | journal = DNA Res. | volume = 5 | issue = 3 | pages = 169–76 |date=June 1998 | pmid = 9734811 | doi = 10.1093/dnares/5.3.169 | doi-access = free }}
  • {{cite journal | vauthors = Dowler S, Currie RA, Campbell DG, Deak M, Kular G, Downes CP, Alessi DR | title = Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities | journal = Biochem. J. | volume = 351 | issue = Pt 1 | pages = 19–31 |date=October 2000 | pmid = 11001876 | pmc = 1221362 | doi = 10.1042/0264-6021:3510019 }}
  • {{cite journal | vauthors = Hotta A, Kawakatsu T, Nakatani T, Sato T, Matsui C, Sukezane T, Akagi T, Hamaji T, Grigoriev I, Akhmanova A, Takai Y, Mimori-Kiyosue Y | title = Laminin-based cell adhesion anchors microtubule plus ends to the epithelial cell basal cortex through LL5alpha/beta | journal = J. Cell Biol. | volume = 189 | issue = 5 | pages = 901–17 |date=May 2010 | pmid = 20513769 | pmc = 2878951 | doi = 10.1083/jcb.200910095 }}

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