PLCD1

Phospholipase C

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• {{cite journal | author=Yagisawa H |title=Nucleocytoplasmic shuttling of phospholipase C-delta1: a link to Ca2+. |journal=J. Cell. Biochem. |volume=97 |issue= 2 |pages= 233–43 |year= 2006 |pmid= 16240320 |doi= 10.1002/jcb.20677 |s2cid=84240929 |doi-access=free }}
• {{cite journal |vauthors=Cefai D, Debre P, Kaczorek M, etal |title=Human immunodeficiency virus-1 glycoproteins gp120 and gp160 specifically inhibit the CD3/T cell-antigen receptor phosphoinositide transduction pathway. |journal=J. Clin. Invest. |volume=86 |issue= 6 |pages= 2117–24 |year= 1991 |pmid= 1979339 |doi=10.1172/JCI114950 | pmc=329852 }}
• {{cite journal |vauthors=Zauli G, Previati M, Caramelli E, etal |title=Exogenous human immunodeficiency virus type-1 Tat protein selectively stimulates a phosphatidylinositol-specific phospholipase C nuclear pathway in the Jurkat T cell line. |journal=Eur. J. Immunol. |volume=25 |issue= 9 |pages= 2695–700 |year= 1995 |pmid= 7589147 |doi=10.1002/eji.1830250944 |s2cid=20562627 }}
• {{cite journal |vauthors=Cheng HF, Jiang MJ, Chen CL, etal |title=Cloning and identification of amino acid residues of human phospholipase C delta 1 essential for catalysis. |journal=J. Biol. Chem. |volume=270 |issue= 10 |pages= 5495–505 |year= 1995 |pmid= 7890667 |doi=10.1074/jbc.270.10.5495 |doi-access=free }}
• {{cite journal |vauthors=Ghosh S, Pawelczyk T, Lowenstein JM |title=Phospholipase C isoforms delta 1 and delta 3 from human fibroblasts. High-yield expression in Escherichia coli, simple purification, and properties. |journal=Protein Expr. Purif. |volume=9 |issue= 2 |pages= 262–78 |year= 1997 |pmid= 9056492 |doi=10.1006/prep.1996.0682 }}
• {{cite journal |vauthors=Chen P, Mayne M, Power C, Nath A |title=The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological diseases. |journal=J. Biol. Chem. |volume=272 |issue= 36 |pages= 22385–8 |year= 1997 |pmid= 9278385 |doi=10.1074/jbc.272.36.22385 |doi-access=free }}
• {{cite journal |vauthors=Park ES, Won JH, Han KJ, etal |title=Phospholipase C-delta1 and oxytocin receptor signalling: evidence of its role as an effector. |journal=Biochem. J. |volume=331 |issue= 1|pages= 283–9 |year= 1998 |pmid= 9512491 |doi= 10.1042/bj3310283| pmc=1219350 }}
• {{cite journal |vauthors=Shimohama S, Kamiya S, Fujii M, etal |title=Mutation in the pleckstrin homology domain of the human phospholipase C-delta 1 gene is associated with loss of function. |journal=Biochem. Biophys. Res. Commun. |volume=245 |issue= 3 |pages= 722–8 |year= 1998 |pmid= 9588182 |doi= 10.1006/bbrc.1998.8307 }}
• {{cite journal |vauthors=Mayne M, Bratanich AC, Chen P, etal |title=HIV-1 tat molecular diversity and induction of TNF-alpha: implications for HIV-induced neurological disease. |journal=Neuroimmunomodulation |volume=5 |issue= 3–4 |pages= 184–92 |year= 1998 |pmid= 9730685 |doi=10.1159/000026336 |s2cid=19529677 }}
• {{cite journal |vauthors=Haughey NJ, Holden CP, Nath A, Geiger JD |title=Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dysregulation and neuron cell death caused by HIV-1 protein tat. |journal=J. Neurochem. |volume=73 |issue= 4 |pages= 1363–74 |year= 1999 |pmid= 10501179 |doi=10.1046/j.1471-4159.1999.0731363.x |s2cid=25410140 |doi-access=free }}
• {{cite journal |vauthors=Mayne M, Holden CP, Nath A, Geiger JD |title=Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages. |journal=J. Immunol. |volume=164 |issue= 12 |pages= 6538–42 |year= 2000 |pmid= 10843712 |doi= 10.4049/jimmunol.164.12.6538|doi-access=free }}
• {{cite journal |vauthors=Nash MS, Young KW, Willars GB, etal |title=Single-cell imaging of graded Ins(1,4,5)P3 production following G-protein-coupled-receptor activation. |journal=Biochem. J. |volume=356 |issue= Pt 1 |pages= 137–42 |year= 2001 |pmid= 11336645 |doi=10.1042/0264-6021:3560137 | pmc=1221821 }}
• {{cite journal |vauthors=Ananthanarayanan B, Das S, Rhee SG, etal |title=Membrane targeting of C2 domains of phospholipase C-delta isoforms. |journal=J. Biol. Chem. |volume=277 |issue= 5 |pages= 3568–75 |year= 2002 |pmid= 11706040 |doi= 10.1074/jbc.M109705200 |doi-access= free }}
• {{cite journal |vauthors=Keshamouni VG, Mattingly RR, Reddy KB |title=Mechanism of 17-beta-estradiol-induced Erk1/2 activation in breast cancer cells. A role for HER2 AND PKC-delta. |journal=J. Biol. Chem. |volume=277 |issue= 25 |pages= 22558–65 |year= 2002 |pmid= 11960991 |doi= 10.1074/jbc.M202351200 |doi-access= free }}
• {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
• {{cite journal |vauthors=Bennasser Y, Badou A, Tkaczuk J, Bahraoui E |title=Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha. |journal=Virology |volume=303 |issue= 1 |pages= 174–80 |year= 2003 |pmid= 12482669 |doi=10.1006/viro.2002.1676 |doi-access=free }}
• {{cite journal |vauthors=Guo Y, Philip F, Scarlata S |title=The Pleckstrin homology domains of phospholipases C-beta and -delta confer activation through a common site. |journal=J. Biol. Chem. |volume=278 |issue= 32 |pages= 29995–30004 |year= 2003 |pmid= 12761218 |doi= 10.1074/jbc.M301438200 |doi-access= free }}
• {{cite journal |vauthors=Caprini M, Gomis A, Cabedo H, etal |title=GAP43 stimulates inositol trisphosphate-mediated calcium release in response to hypotonicity. |journal=EMBO J. |volume=22 |issue= 12 |pages= 3004–14 |year= 2003 |pmid= 12805215 |doi= 10.1093/emboj/cdg294 | pmc=162146 }}
• {{cite journal |vauthors=Kim JY, Kim H, Lee SG, etal |title=Amyloid beta peptide (Abeta42) activates PLC-delta1 promoter through the NF-kappaB binding site. |journal=Biochem. Biophys. Res. Commun. |volume=310 |issue= 3 |pages= 904–9 |year= 2003 |pmid= 14550290 |doi=10.1016/j.bbrc.2003.09.100 }}

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• [http://www.wikigenes.org/e/gene/e/24655.html WikiGenes entry for PLCD1]

{{PDB Gallery|geneid=5333}}

{{Esterases}}

{{Enzymes}}

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Category:EC 3.1.4

Category:EF-hand-containing proteins

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