PLCD4
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4 is an enzyme that in humans is encoded by the PLCD4 gene.{{cite journal |vauthors=Kim H, Suh PG, Ryu SH, Park SH | title = Assignment of the human PLC delta4 gene (PLCD4) to human chromosome band 2q35 by fluorescence in situ hybridization | journal = Cytogenet Cell Genet | volume = 87 | issue = 3–4 | pages = 254–5 |date=Apr 2000 | pmid = 10702683 | doi =10.1159/000015437 | s2cid = 40877378 }}{{cite journal |vauthors=Ghosh S, Pawelczyk T, Lowenstein JM | title = Phospholipase C isoforms delta 1 and delta 3 from human fibroblasts. High-yield expression in Escherichia coli, simple purification, and properties | journal = Protein Expr Purif | volume = 9 | issue = 2 | pages = 262–78 |date=Jun 1997 | pmid = 9056492 | doi = 10.1006/prep.1996.0682}}{{cite web | title = Entrez Gene: PLCD4 phospholipase C, delta 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84812}}
References
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Further reading
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- {{cite journal |vauthors=Cefai D, Debre P, Kaczorek M, etal |title=Human immunodeficiency virus-1 glycoproteins gp120 and gp160 specifically inhibit the CD3/T cell-antigen receptor phosphoinositide transduction pathway |journal=J. Clin. Invest. |volume=86 |issue= 6 |pages= 2117–24 |year= 1991 |pmid= 1979339 |doi=10.1172/JCI114950 | pmc=329852 }}
- {{cite journal |vauthors=Zauli G, Previati M, Caramelli E, etal |title=Exogenous human immunodeficiency virus type-1 Tat protein selectively stimulates a phosphatidylinositol-specific phospholipase C nuclear pathway in the Jurkat T cell line |journal=Eur. J. Immunol. |volume=25 |issue= 9 |pages= 2695–700 |year= 1995 |pmid= 7589147 |doi=10.1002/eji.1830250944 |s2cid=20562627 }}
- {{cite journal |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
- {{cite journal |vauthors=Chen P, Mayne M, Power C, Nath A |title=The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological diseases |journal=J. Biol. Chem. |volume=272 |issue= 36 |pages= 22385–8 |year= 1997 |pmid= 9278385 |doi=10.1074/jbc.272.36.22385 |doi-access=free }}
- {{cite journal |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 }}
- {{cite journal |vauthors=Mayne M, Bratanich AC, Chen P, etal |title=HIV-1 tat molecular diversity and induction of TNF-alpha: implications for HIV-induced neurological disease |journal=Neuroimmunomodulation |volume=5 |issue= 3–4 |pages= 184–92 |year= 1998 |pmid= 9730685 |doi=10.1159/000026336 |s2cid=19529677 }}
- {{cite journal |vauthors=Haughey NJ, Holden CP, Nath A, Geiger JD |title=Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dysregulation and neuron cell death caused by HIV-1 protein tat |journal=J. Neurochem. |volume=73 |issue= 4 |pages= 1363–74 |year= 1999 |pmid= 10501179 |doi=10.1046/j.1471-4159.1999.0731363.x |s2cid=25410140 |doi-access= }}
- {{cite journal |vauthors=Mayne M, Holden CP, Nath A, Geiger JD |title=Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages |journal=J. Immunol. |volume=164 |issue= 12 |pages= 6538–42 |year= 2000 |pmid= 10843712 |doi= 10.4049/jimmunol.164.12.6538|doi-access=free }}
- {{cite journal |vauthors=Ananthanarayanan B, Das S, Rhee SG, etal |title=Membrane targeting of C2 domains of phospholipase C-delta isoforms |journal=J. Biol. Chem. |volume=277 |issue= 5 |pages= 3568–75 |year= 2002 |pmid= 11706040 |doi= 10.1074/jbc.M109705200 |doi-access= free }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal |vauthors=Bennasser Y, Badou A, Tkaczuk J, Bahraoui E |title=Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha |journal=Virology |volume=303 |issue= 1 |pages= 174–80 |year= 2003 |pmid= 12482669 |doi=10.1006/viro.2002.1676 |doi-access=free }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |doi-access= free }}
- {{cite journal |vauthors=Lee SB, Várnai P, Balla A, etal |title=The pleckstrin homology domain of phosphoinositide-specific phospholipase Cdelta4 is not a critical determinant of the membrane localization of the enzyme |journal=J. Biol. Chem. |volume=279 |issue= 23 |pages= 24362–71 |year= 2004 |pmid= 15037625 |doi= 10.1074/jbc.M312772200 |doi-access= free }}
- {{cite journal |vauthors=Leung DW, Tompkins C, Brewer J, etal |title=Phospholipase C δ-4 overexpression upregulates ErbB1/2 expression, Erk signaling pathway, and proliferation in MCF-7 cells |journal=Mol. Cancer |volume=3 |pages= 15 |year= 2004 |pmid= 15140260 |doi= 10.1186/1476-4598-3-15 | pmc=420486 |doi-access=free }}
- {{cite journal |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |bibcode=2005Natur.437.1173R |s2cid=4427026 }}
- {{cite journal |vauthors=Chae SW, Kim JM, Yun YP, etal |title=Identification and analysis of the promoter region of the human PLC-delta4 gene |journal=Mol. Biol. Rep. |volume=34 |issue= 2 |pages= 69–77 |year= 2007 |pmid= 17394098 |doi= 10.1007/s11033-006-9014-x |s2cid=24577383 }}
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{{Esterases}}
{{Enzymes}}
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Category:EF-hand-containing proteins
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