PLRG1
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Pleiotropic regulator 1 is a protein that in humans is encoded by the PLRG1 gene.{{cite web | title = Entrez Gene: PLRG1 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5356| accessdate = }}
Interactions
PLRG1 has been shown to interact with CDC5L.{{cite journal |vauthors=Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D |year=2007|title=Large-scale mapping of human protein-protein interactions by mass spectrometry |journal=Mol. Syst. Biol. |volume=3 |issue= 1|pages=89 | pmid = 17353931 |doi = 10.1038/msb4100134 |pmc=1847948 }}{{cite journal |vauthors=Ajuh P, Lamond AI |date=November 2003 |title=Identification of peptide inhibitors of pre-mRNA splicing derived from the essential interaction domains of CDC5L and PLRG1 |journal=Nucleic Acids Res. |volume=31 |issue=21 |pages=6104–16 | pmid = 14576297 |doi=10.1093/nar/gkg817 |pmc=275459 }}{{cite journal |vauthors=Ajuh P, Sleeman J, Chusainow J, Lamond AI |date=November 2001 |title=A direct interaction between the carboxyl-terminal region of CDC5L and the WD40 domain of PLRG1 is essential for pre-mRNA splicing |journal=J. Biol. Chem. |volume=276 |issue=45 |pages=42370–81 | issn = 0021-9258| pmid = 11544257 |doi = 10.1074/jbc.M105453200 |doi-access=free }}{{cite journal |vauthors=Ajuh P, Kuster B, Panov K, Zomerdijk JC, Mann M, Lamond AI |title=Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry |journal=EMBO J. |volume=19 |issue=23 |pages=6569–81 |year=2000 |pmid=11101529 |pmc=305846 |doi=10.1093/emboj/19.23.6569 }}
References
{{reflist}}
Further reading
{{refbegin | 2}}
- {{cite journal | author=Németh K |title=Pleiotropic control of glucose and hormone responses by PRL1, a nuclear WD protein, in Arabidopsis |journal=Genes Dev. |volume=12 |issue= 19 |pages= 3059–73 |year= 1998 |pmid= 9765207 |doi=10.1101/gad.12.19.3059 | pmc=317193 |name-list-style=vanc| author2=Salchert K | author3=Putnoky P | display-authors=3 | last4=Bhalerao | first4=R. | last5=Koncz-Kalman | first5=Z. | last6=Stankovic-Stangeland | first6=B. | last7=Bako | first7=L. | last8=Mathur | first8=J. | last9=Okresz | first9=L. }}
- {{cite journal | author=Ajuh P |title=Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry |journal=EMBO J. |volume=19 |issue= 23 |pages= 6569–81 |year= 2001 |pmid= 11101529 |doi= 10.1093/emboj/19.23.6569 | pmc=305846 |name-list-style=vanc| author2=Kuster B | author3=Panov K | display-authors=3 | last4=Zomerdijk | first4=JC | last5=Mann | first5=M | last6=Lamond | first6=AI }}
- {{cite journal |vauthors=Ajuh P, Sleeman J, Chusainow J, Lamond AI |title=A direct interaction between the carboxyl-terminal region of CDC5L and the WD40 domain of PLRG1 is essential for pre-mRNA splicing |journal=J. Biol. Chem. |volume=276 |issue= 45 |pages= 42370–81 |year= 2001 |pmid= 11544257 |doi= 10.1074/jbc.M105453200 |doi-access= free }}
- {{cite journal |vauthors=Rappsilber J, Ryder U, Lamond AI, Mann M |title=Large-scale proteomic analysis of the human spliceosome |journal=Genome Res. |volume=12 |issue= 8 |pages= 1231–45 |year= 2002 |pmid= 12176931 |doi= 10.1101/gr.473902 | pmc=186633 }}
- {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-style=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD |bibcode=2002PNAS...9916899M|doi-access=free }}
- {{cite journal |vauthors=Ajuh P, Lamond AI |title=Identification of peptide inhibitors of pre-mRNA splicing derived from the essential interaction domains of CDC5L and PLRG1 |journal=Nucleic Acids Res. |volume=31 |issue= 21 |pages= 6104–16 |year= 2003 |pmid= 14576297 |doi=10.1093/nar/gkg817 | pmc=275459 }}
- {{cite journal | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |name-list-style=vanc| author2=Suzuki Y | author3=Nishikawa T | display-authors=3 | last4=Otsuki | first4=Tetsuji | last5=Sugiyama | first5=Tomoyasu | last6=Irie | first6=Ryotaro | last7=Wakamatsu | first7=Ai | last8=Hayashi | first8=Koji | last9=Sato | first9=Hiroyuki | doi-access=free }}
- {{cite journal | author=Gerhard DS |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-style=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}
- {{cite journal | author=Andersen JS |title=Nucleolar proteome dynamics |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207 |name-list-style=vanc| author2=Lam YW | author3=Leung AK | display-authors=3 | last4=Ong | first4=Shao-En | last5=Lyon | first5=Carol E. | last6=Lamond | first6=Angus I. | last7=Mann | first7=Matthias |bibcode=2005Natur.433...77A|s2cid=4344740 }}
- {{cite journal | author=Ewing RM |title=Large-scale mapping of human protein-protein interactions by mass spectrometry |journal=Mol. Syst. Biol. |volume=3 |issue= 1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 | pmc=1847948 |name-list-style=vanc| author2=Chu P | author3=Elisma F | display-authors=3 | last4=Li | first4=Hongyan | last5=Taylor | first5=Paul | last6=Climie | first6=Shane | last7=McBroom-Cerajewski | first7=Linda | last8=Robinson | first8=Mark D | last9=O'Connor | first9=Liam }}
{{refend}}
{{Post transcriptional modification}}
{{gene-4-stub}}