PPP3R2
{{Short description|Protein-coding gene in the species Homo sapiens}}
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Calcineurin subunit B type 2 is a protein that in humans is encoded by the PPP3R2 gene.{{cite journal | vauthors = Liu L, Zhang J, Yuan J, Dang Y, Yang C, Chen X, Xu J, Yu L | title = Characterization of a human regulatory subunit of protein phosphatase 3 gene (PPP3RL) expressed specifically in testis | journal = Mol Biol Rep | volume = 32 | issue = 1 | pages = 41–5 |date=May 2005 | pmid = 15865209 | doi =10.1007/s11033-004-4250-4 | s2cid = 43848098 }}{{cite web | title = Entrez Gene: PPP3R2 protein phosphatase 3 (formerly 2B), regulatory subunit B, beta isoform| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5535}} Among its related pathways are MAPK signaling pathway{{Cite web|title = PathCards :: MAPK signaling pathway Pathway and related pathways|url = http://pathcards.genecards.org/card/mapk_signaling_pathway|website = pathcards.genecards.org|access-date = 2015-09-08}} and GPCR pathway.{{Cite web|title = PathCards :: GPCR Pathway Pathway and related pathways|url = http://pathcards.genecards.org/card/gpcr_pathway|website = pathcards.genecards.org|access-date = 2015-09-08}} GO annotations related to this gene include calcium ion binding. An important paralog of this gene is CHP1.{{Cite web|title = PPP3R2 Gene - GeneCards {{!}} CANB2 Protein {{!}} CANB2 Antibody|url = https://www.genecards.org/cgi-bin/carddisp.pl?gene=PPP3R2|website = www.genecards.org|access-date = 2015-09-08|first = GeneCards Human Gene|last = Database}}
References
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Further reading
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- {{cite journal |vauthors=Mukai H, Chang CD, Tanaka H, etal |title=cDNA cloning of a novel testis-specific calcineurin B-like protein. |journal=Biochem. Biophys. Res. Commun. |volume=179 |issue= 3 |pages= 1325–30 |year= 1991 |pmid= 1718268 |doi=10.1016/0006-291X(91)91718-R }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal | vauthors=Bennasser Y, Badou A, Tkaczuk J, Bahraoui E |title=Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha |journal=Virology |volume=303 |issue= 1 |pages= 174–80 |year= 2003 |pmid= 12482669 |doi=10.1006/viro.2002.1676 |doi-access=free }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |doi-access= free }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Koefoed-Nielsen PB, Karamperis N, Højskov C, etal |title=The calcineurin activity profiles of cyclosporin and tacrolimus are different in stable renal transplant patients |journal=Transpl. Int. |volume=19 |issue= 10 |pages= 821–7 |year= 2007 |pmid= 16961774 |doi= 10.1111/j.1432-2277.2006.00359.x |s2cid=1891740 }}
- {{cite journal |vauthors=Saeki M, Irie Y, Ni L, etal |title=Calcineurin potentiates the activation of procaspase-3 by accelerating its proteolytic maturation |journal=J. Biol. Chem. |volume=282 |issue= 16 |pages= 11786–94 |year= 2007 |pmid= 17324936 |doi= 10.1074/jbc.M609347200 |doi-access= free }}
- {{cite journal | vauthors=Jang H, Cho EJ, Youn HD |title=A new calcineurin inhibition domain in Cabin1 |journal=Biochem. Biophys. Res. Commun. |volume=359 |issue= 1 |pages= 129–35 |year= 2007 |pmid= 17531200 |doi= 10.1016/j.bbrc.2007.05.066 }}
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