PPP5C

PPP5C has been shown to interact with ASK1,{{cite journal | vauthors = Morita K, Saitoh M, Tobiume K, Matsuura H, Enomoto S, Nishitoh H, Ichijo H | title = Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress | journal = The EMBO Journal | volume = 20 | issue = 21 | pages = 6028–36 | date = Nov 2001 | pmid = 11689443 | pmc = 125685 | doi = 10.1093/emboj/20.21.6028 }} CRY2{{cite journal | vauthors = Zhao S, Sancar A | title = Human blue-light photoreceptor hCRY2 specifically interacts with protein serine/threonine phosphatase 5 and modulates its activity | journal = Photochemistry and Photobiology | volume = 66 | issue = 5 | pages = 727–31 | date = Nov 1997 | pmid = 9383998 | doi = 10.1111/j.1751-1097.1997.tb03214.x | s2cid = 32804361 }} GNA12.{{cite journal | vauthors = Yamaguchi Y, Katoh H, Mori K, Negishi M | title = Galpha(12) and Galpha(13) interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity | journal = Current Biology | volume = 12 | issue = 15 | pages = 1353–8 | date = Aug 2002 | pmid = 12176367 | doi = 10.1016/S0960-9822(02)01034-5 | s2cid = 11485795 | doi-access = free }} and Rac1,{{cite journal | vauthors = Chatterjee A, Wang L, Armstrong DL, Rossie S | title = Activated Rac1 GTPase translocates protein phosphatase 5 to the cell membrane and stimulates phosphatase activity in vitro | journal = The Journal of Biological Chemistry | volume = 285 | issue = 6 | pages = 3872–82 | date = Feb 2010 | pmid = 19948726 | pmc = 2823530 | doi = 10.1074/jbc.M109.088427 | doi-access = free }}

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• {{cite journal | vauthors = Chen MX, McPartlin AE, Brown L, Chen YH, Barker HM, Cohen PT | title = A novel human protein serine/threonine phosphatase, which possesses four tetratricopeptide repeat motifs and localizes to the nucleus | journal = The EMBO Journal | volume = 13 | issue = 18 | pages = 4278–90 | date = Sep 1994 | pmid = 7925273 | pmc = 395355 | doi = 10.1002/j.1460-2075.1994.tb06748.x}}
• {{cite journal | vauthors = Skinner J, Sinclair C, Romeo C, Armstrong D, Charbonneau H, Rossie S | title = Purification of a fatty acid-stimulated protein-serine/threonine phosphatase from bovine brain and its identification as a homolog of protein phosphatase 5 | journal = The Journal of Biological Chemistry | volume = 272 | issue = 36 | pages = 22464–71 | date = Sep 1997 | pmid = 9278397 | doi = 10.1074/jbc.272.36.22464 | doi-access = free }}
• {{cite journal | vauthors = Shah BH, Catt KJ | title = Protein phosphatase 5 as a negative key regulator of Raf-1 activation | journal = Trends in Endocrinology and Metabolism | volume = 17 | issue = 10 | pages = 382–4 | date = Dec 2006 | pmid = 17084641 | doi = 10.1016/j.tem.2006.10.013 | s2cid = 45060016 }}
• {{cite journal | vauthors = Goedert M, Cohen ES, Jakes R, Cohen P | title = p42 MAP kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1. Implications for Alzheimer's disease [corrected] | journal = FEBS Letters | volume = 312 | issue = 1 | pages = 95–9 | date = Nov 1992 | pmid = 1330687 | doi = 10.1016/0014-5793(92)81418-L | s2cid = 34940651 | doi-access = free }}
• {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1–2 | pages = 171–4 | date = Jan 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
• {{cite journal | vauthors = Xu X, Lagercrantz J, Zickert P, Bajalica-Lagercrantz S, Zetterberg A | title = Chromosomal localization and 5' sequence of the human protein serine/threonine phosphatase 5' gene | journal = Biochemical and Biophysical Research Communications | volume = 218 | issue = 2 | pages = 514–7 | date = Jan 1996 | pmid = 8561788 | doi = 10.1006/bbrc.1996.0092 }}
• {{cite journal | vauthors = Silverstein AM, Galigniana MD, Chen MS, Owens-Grillo JK, Chinkers M, Pratt WB | title = Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin | journal = The Journal of Biological Chemistry | volume = 272 | issue = 26 | pages = 16224–30 | date = Jun 1997 | pmid = 9195923 | doi = 10.1074/jbc.272.26.16224 | doi-access = free }}
• {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1–2 | pages = 149–56 | date = Oct 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
• {{cite journal | vauthors = Zhao S, Sancar A | title = Human blue-light photoreceptor hCRY2 specifically interacts with protein serine/threonine phosphatase 5 and modulates its activity | journal = Photochemistry and Photobiology | volume = 66 | issue = 5 | pages = 727–31 | date = Nov 1997 | pmid = 9383998 | doi = 10.1111/j.1751-1097.1997.tb03214.x | s2cid = 32804361 }}
• {{cite journal | vauthors = Ollendorff V, Donoghue DJ | title = The serine/threonine phosphatase PP5 interacts with CDC16 and CDC27, two tetratricopeptide repeat-containing subunits of the anaphase-promoting complex | journal = The Journal of Biological Chemistry | volume = 272 | issue = 51 | pages = 32011–8 | date = Dec 1997 | pmid = 9405394 | doi = 10.1074/jbc.272.51.32011 | doi-access = free }}
• {{cite journal | vauthors = Das AK, Cohen PW, Barford D | title = The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR-mediated protein-protein interactions | journal = The EMBO Journal | volume = 17 | issue = 5 | pages = 1192–9 | date = Mar 1998 | pmid = 9482716 | pmc = 1170467 | doi = 10.1093/emboj/17.5.1192 }}
• {{cite journal | vauthors = Russell LC, Whitt SR, Chen MS, Chinkers M | title = Identification of conserved residues required for the binding of a tetratricopeptide repeat domain to heat shock protein 90 | journal = The Journal of Biological Chemistry | volume = 274 | issue = 29 | pages = 20060–3 | date = Jul 1999 | pmid = 10400612 | doi = 10.1074/jbc.274.29.20060 | doi-access = free }}
• {{cite journal | vauthors = Lubert EJ, Hong Y, Sarge KD | title = Interaction between protein phosphatase 5 and the A subunit of protein phosphatase 2A: evidence for a heterotrimeric form of protein phosphatase 5 | journal = The Journal of Biological Chemistry | volume = 276 | issue = 42 | pages = 38582–7 | date = Oct 2001 | pmid = 11504734 | doi = 10.1074/jbc.M106906200 | doi-access = free }}
• {{cite journal | vauthors = Morita K, Saitoh M, Tobiume K, Matsuura H, Enomoto S, Nishitoh H, Ichijo H | title = Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress | journal = The EMBO Journal | volume = 20 | issue = 21 | pages = 6028–36 | date = Nov 2001 | pmid = 11689443 | pmc = 125685 | doi = 10.1093/emboj/20.21.6028 }}
• {{cite journal | vauthors = Sanchez-Ortiz E, Hahm BK, Armstrong DL, Rossie S | title = Protein phosphatase 5 protects neurons against amyloid-beta toxicity | journal = Journal of Neurochemistry | volume = 111 | issue = 2 | pages = 391–402 | date = Oct 2009 | pmid = 19686245 | pmc = 3044491 | doi = 10.1111/j.1471-4159.2009.06337.x }}
• {{cite journal | vauthors = Yamaguchi Y, Katoh H, Mori K, Negishi M | title = Galpha(12) and Galpha(13) interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity | journal = Current Biology | volume = 12 | issue = 15 | pages = 1353–8 | date = Aug 2002 | pmid = 12176367 | doi = 10.1016/S0960-9822(02)01034-5 | s2cid = 11485795 | doi-access = free }}
• {{cite journal | vauthors = Gentile S, Darden T, Erxleben C, Romeo C, Russo A, Martin N, Rossie S, Armstrong DL | title = Rac GTPase signaling through the PP5 protein phosphatase | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 103 | issue = 13 | pages = 5202–6 | date = Mar 2006 | pmid = 16549782 | pmc = 1458818 | doi = 10.1073/pnas.0600080103 | bibcode = 2006PNAS..103.5202G | doi-access = free }}
• {{cite journal | vauthors = Liu F, Zaidi T, Iqbal K, Grundke-Iqbal I, Gong CX | title = Aberrant glycosylation modulates phosphorylation of tau by protein kinase A and dephosphorylation of tau by protein phosphatase 2A and 5 | journal = Neuroscience | volume = 115 | issue = 3 | pages = 829–37 | year = 2003 | pmid = 12435421 | doi = 10.1016/S0306-4522(02)00510-9 | s2cid = 26118803 }}
• {{cite journal | vauthors = Urban G, Golden T, Aragon IV, Cowsert L, Cooper SR, Dean NM, Honkanen RE | title = Identification of a functional link for the p53 tumor suppressor protein in dexamethasone-induced growth suppression | journal = The Journal of Biological Chemistry | volume = 278 | issue = 11 | pages = 9747–53 | date = Mar 2003 | pmid = 12519780 | doi = 10.1074/jbc.M210993200 | doi-access = free }}
• {{cite journal | vauthors = Tomsig JL, Snyder SL, Creutz CE | title = Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif | journal = The Journal of Biological Chemistry | volume = 278 | issue = 12 | pages = 10048–54 | date = Mar 2003 | pmid = 12522145 | doi = 10.1074/jbc.M212632200 | doi-access = free }}
• {{cite journal | vauthors = Matsuda A, Suzuki Y, Honda G, Muramatsu S, Matsuzaki O, Nagano Y, Doi T, Shimotohno K, Harada T, Nishida E, Hayashi H, Sugano S | title = Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways | journal = Oncogene | volume = 22 | issue = 21 | pages = 3307–18 | date = May 2003 | pmid = 12761501 | doi = 10.1038/sj.onc.1206406 | s2cid = 38880905 | doi-access = }}

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{{PDB Gallery|geneid=5536}}

Category:Genes mutated in mice