PTBP2
{{Short description|Protein-coding gene in the species Homo sapiens}}
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Polypyrimidine tract binding protein 2, also known as PTBP2, is a protein which in humans is encoded by the PTBP2 gene.{{cite journal | vauthors = Markovtsov V, Nikolic JM, Goldman JA, Turck CW, Chou MY, Black DL | title = Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein | journal = Mol. Cell. Biol. | volume = 20 | issue = 20 | pages = 7463–79 |date=October 2000 | pmid = 11003644 | pmc = 86300 | doi = 10.1128/MCB.20.20.7463-7479.2000}}{{cite web | title = Entrez Gene: PTBP2 polypyrimidine tract binding protein 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=58155 }}
Function
The protein encoded by this gene binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract-binding protein PTBP1 but it is expressed primarily in the brain.
References
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