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PYGO2

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Pygopus homolog 2 is a protein that in humans is encoded by the PYGO2 gene.{{cite journal | vauthors = Thompson B, Townsley F, Rosin-Arbesfeld R, Musisi H, Bienz M | title = A new nuclear component of the Wnt signalling pathway | journal = Nat Cell Biol | volume = 4 | issue = 5 | pages = 367–73 |date=May 2002 | pmid = 11988739 | doi = 10.1038/ncb786 | s2cid = 23942463 }}{{cite web | title = Entrez Gene: PYGO2 pygopus homolog 2 (Drosophila)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=90780}}

References

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Further reading

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  • {{cite journal |vauthors=Kramps T, Peter O, Brunner E, etal |title=Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex. |journal=Cell |volume=109 |issue=1 |pages=47–60 |year=2002 |pmid=11955446 |doi=10.1016/S0092-8674(02)00679-7 |s2cid=16720801 |url=https://www.zora.uzh.ch/id/eprint/966/1/Krawnt02v.pdf |access-date=2021-01-31 |archive-date=2021-09-26 |archive-url=https://web.archive.org/web/20210926074127/https://www.zora.uzh.ch/id/eprint/966/1/Krawnt02v.pdf |url-status=dead }}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal | vauthors=Townsley FM, Thompson B, Bienz M |title=Pygopus residues required for its binding to Legless are critical for transcription and development |journal=J. Biol. Chem. |volume=279 |issue= 7 |pages= 5177–83 |year= 2004 |pmid= 14612447 |doi= 10.1074/jbc.M309722200 |s2cid=6880212 |doi-access=free }}
  • {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |s2cid=21903526 |doi-access=free }}
  • {{cite journal |vauthors=Brandenberger R, Wei H, Zhang S, etal |title=Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation |journal=Nat. Biotechnol. |volume=22 |issue= 6 |pages= 707–16 |year= 2005 |pmid= 15146197 |doi= 10.1038/nbt971 |s2cid=27764390 }}
  • {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
  • {{cite journal |vauthors=Wan D, Gong Y, Qin W, etal |title=Large-scale cDNA transfection screening for genes related to cancer development and progression |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 44 |pages= 15724–9 |year= 2004 |pmid= 15498874 |doi= 10.1073/pnas.0404089101 | pmc=524842 |bibcode=2004PNAS..10115724W |doi-access=free }}
  • {{cite journal |vauthors=Popadiuk CM, Xiong J, Wells MG, etal |title=Antisense suppression of pygopus2 results in growth arrest of epithelial ovarian cancer |journal=Clin. Cancer Res. |volume=12 |issue= 7 Pt 1 |pages= 2216–23 |year= 2006 |pmid= 16609037 |doi= 10.1158/1078-0432.CCR-05-2433 |s2cid=3260972 |doi-access=free }}
  • {{cite journal |vauthors=Beausoleil SA, Villén J, Gerber SA, etal |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 |s2cid=14294292 }}
  • {{cite journal | vauthors=Hoffmans R, Basler K |title=BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling |journal=Mech. Dev. |volume=124 |issue= 1 |pages= 59–67 |year= 2007 |pmid= 17113272 |doi= 10.1016/j.mod.2006.09.006 |s2cid=17642255 |doi-access=free }}
  • {{cite journal | vauthors=Andrews PG, Lake BB, Popadiuk C, Kao KR |title=Requirement of Pygopus 2 in breast cancer |journal=Int. J. Oncol. |volume=30 |issue= 2 |pages= 357–63 |year= 2007 |pmid= 17203217 |doi= 10.3892/ijo.30.2.357 |doi-broken-date=1 November 2024 }}

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