Parathion S
{{Chembox
| Name = Parathion S
| ImageFile = Parathion S.svg
| ImageSize = 200px
| PIN = O,O-Diethyl S-(4-nitrophenyl) phosphorothioate
| OtherNames = S-Phenyl parathion
| Section1 = {{Chembox Identifiers
| CASNo = 3270-86-8
| ChemSpiderID = 2297420
| PubChem = 3032440
| SMILES = CCOP(=O)(OCC)Sc1ccc(cc1)[N+](=O)[O-]
| StdInChI = InChI=1S/C10H14NO5PS/c1-3-15-17(14,16-4-2)18-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3
| StdInChIKey = DSVCXDBXXBVSEB-UHFFFAOYSA-N
}}
| Section2 = {{Chembox Properties
| C=10|H=14|N=1|O=5|P=1|S=1
| Appearance = Pale yellow crystalline solid
}}
| Section3 = {{Chembox Hazards
| LD50 = 107 μg/kg (mice, intraperitoneal){{cite web |title=ChemIDplus |url=https://chem.nlm.nih.gov/chemidplus/rn/3270-86-8}}
4.41 mg/kg (rats, oral)
}}
}}
Parathion S is an organophosphate related to the organophosphate insecticide paraoxon and parathion. It's the structural isomer of parathion. Parathion S is a potent acetylcholinesterase inhibitor.{{cite journal |last1=DIGGLE |first1=WM |last2=GAGE |first2=JC |title=Cholinesterase inhibition in vitro by OO-diethyl O-p-nitrophenyl thiophosphate (parathion, E 605). |journal=The Biochemical Journal |date=September 1951 |volume=49 |issue=4 |pages=491–4 |pmid=14886312 |pmc=1197537|doi=10.1042/bj0490491 }}{{cite journal |last1=ALDRIDGE |first1=WN |last2=DAVISON |first2=AN |title=The inhibition of erythrocyte cholinesterase by tri-esters of phosphoric acid. II. Diethyl p-nitrophenyl thionphosphate (E605) and analogues. |journal=The Biochemical Journal |date=December 1952 |volume=52 |issue=4 |pages=663–71 |pmid=13018298 |pmc=1198077|doi=10.1042/bj0520663 }}
See also
References
{{reflist}}
{{Acetylcholine metabolism and transport modulators}}
Category:Acetylcholinesterase inhibitors
Category:Organothiophosphate esters
Category:4-Nitrophenyl compounds
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