Paweł Kisielow
{{Short description|Polish immunologist (born 1945)}}
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{{Infobox scientist
| name = Paweł Kisielow
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| birth_date = {{birth date and age|1945|02|21}}
| birth_place = Gorlice, Poland
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| nationality = Polish
| known_for = research on T cells
| awards = {{Plainlist|
- Körber European Science Prize (1997)
- Jurzykowski Prize (1992)
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| workplaces = Polish Academy of Sciences
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Paweł Kisielow (Polish: {{IPAc-pl|'|p|a|w|e|ł|-|k|i|'|ś|e|l|o|w}}; born 21 February 1945 in Gorlice, Poland) is a Polish biologist who specializes in immunology. He is best known for his research on T cells. He is a corresponding member of the Polish Academy of Sciences and a member of the Polish Academy of Arts and Sciences.{{Cite web |url=https://nauka-polska.pl/#/profile/scientist?id=66468&_k=kmjgw5 |language=pl |title=prof. dr hab. czł. koresp. PAN Paweł Kisielow |website=nauka-polska.pl |access-date=5 July 2024}}
Career
He graduated in biology from the Adam Mickiewicz University in Poznań and received a doctoral degree in 1971.{{Cite web |url=https://teatrnn.pl/leksykon/artykuly/rodzina-kisielow/ |language=pl |title=Paweł Kisielow |website=teatrnn.pl |access-date=5 July 2024}} He became a professor in 1987. He works at the Hirszfeld Institute of Immunology and Experimental Therapy of the Polish Academy of Sciences.{{Cite web |url=https://pan.pl/czlonkowie/kisielow_pawel/ |language=pl |title=Paweł Kisielow |website=pan.pl |access-date=5 July 2024}}
In 1992, he received the Jurzykowski Prize conferred by the Alfred Jurzykowski Foundation in New York.
In 1997, he was awarded the Körber European Science Prize jointly with Klaus Rajewsky and Harald von Boehmer for their work on mutant mouse models in clinical research. His scientific contributions have made significant progress towards better understanding the defense system leading to the development of treatments to support a weakened immune system, to combat
cancer and to deal with autoimmune diseases.{{Cite web |url=https://koerber-stiftung.de/site/assets/files/18911/koerber_prize_1997_mutant_mouse_models_in_clinical_research.pdf |title=Körber European Science Prize 1997 |website=koerber-stiftung.de |access-date=5 July 2024}}
In 2003, he became the recipient of the Prime Minister Award for his outstanding scientific output.
Selected publications
- How does the immune system learn to distinguish between good and evil? The first definitive studies of T cell central tolerance and positive selection (2019){{Cite web |url=https://www.researchgate.net/scientific-contributions/Pawel-Kisielow-38253173 |title=Pawel Kisielow's research while affiliated with Polish Academy of Sciences and other places |website=researchgate.net |access-date=5 July 2024}}
- The evolutionary conservation of the bidirectional activity of the NWC gene promoter in jawed vertebrates and the domestication of the RAG transposon (with Lukasz Sniezewski, Sylwia Janik, Agnieszka Łaszkiewicz, Malgorzata Cebrat, 2017)
- Anti-GITR Antibody Treatment Increases TCR Repertoire Diversity of Regulatory but not Effector T Cells Engaged in the Immune Response Against B16 Melanoma (with Bozena Scirka, Edyta Anna Szurek, Maciej Pietrzak, Arkadiusz Miazek, 2017)
- Search for the Function of NWC, Third Gene Within RAG Locus: Generation and Characterization of NWC-Deficient Mice (with Monika Kasztura, Lukasz Sniezewski, Agnieszka Łaszkiewicz, 2015)
See also
References
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