Peter Tishler
{{Short description|American physician and academic}}
Peter Verveer Tishler (July 18, 1937 – January 18, 2021) was a researcher in human genetics and orphan diseases, educator, and clinician especially in the areas of genetic diseases, including polycystic kidney disease, chronic obstructive pulmonary disease, Fabry disease, and the porphyrias.
Biography
Tishler was born on July 18, 1937, in Boston, Massachusetts to Max Tishler and Elizabeth M. Verveer, and grew up in New Jersey. He passed away January 18, 2021, in Watertown, New York.{{cite book |title=Inventors and Inventions |page=1082 |quote=On June 17, 1934, he married Elizabeth M. Verveer, who had been a student in his freshman chemistry laboratory at Tufts. The couple had two sons, Peter Verveer Tishler (b. 1937), a physician and genetics researcher, and Carl Lewis Tishler ... }}{{cite book |author=Kristine M. Krapp |title=Notable Twentieth Century Scientists |year= 1998 |isbn=9780787627669 |quote=They had two sons during their marriage, Peter Verveer Tishler, who went on to become a noted physician specializing in the genetics associated with diseases, and Carl Lewis Tishler. | url=https://books.google.com/books?id=xD8OAQAAMAAJ&q=Peter+Tishler }}{{cite news |title=Max Tishler Is Dead. Pioneer in Making Of Cortisone Was 82 |url=https://www.nytimes.com/1989/03/20/obituaries/max-tishler-is-dead-pioneer-in-making-of-cortisone-was-82.html |quote=Surviving are his wife, Elizabeth, of Middletown; two sons, Peter, of Boston and Carl, of Columbus, Ohio; and three grandchildren. |newspaper=New York Times |date=March 20, 1989 |access-date=2015-04-10 }}
Tishler attended public schools and Harvard College where he majored in biochemistry. He wrote his senior thesis on carboxypeptidase, in the lab of Dr. C.J. Fu at the Jimmy Fund, graduating cum laude in 1959.
Tishler attended Yale School of Medicine and graduated in 1962.{{cite book |title=In Quest of Panacea |year=1987 |isbn=9788190004107 |quote=Peter Tishler graduated medical school in 1962. ... | url=https://books.google.com/books?id=Re1qAAAAMAAJ&q=Peter+Tishler |last1=Gupta |first1=Sikharam Prasanna Kumara |last2=Milford |first2=Edgar L. |publisher=Evelyn Publishers }} While at Yale, Tishler began working with the Thorndike Memorial Laboratory at Boston City Hospital from 1963 to 1977.{{cite book |title=The Harvard Medical Unit at Boston City Hospital |page=1188 | url=https://books.google.com/books?id=UFxrAAAAMAAJ&q=%22Peter+V.+Tishler%22 |last1=Finland |first1=Maxwell |year=1982 }}
William B. Castle, discoverer of intrinsic factor, introduced him to Sidney H. Ingbar with whom Tishler began work on the metabolic actions of thyroid hormone. Maxwell Finland contributed to Tishler's scientific and clinical work.Finland, Maxwell and Castle, William B., Eds. (1983) The Harvard Medical Unit at Boston City Hospital, Volume II. University of Virginia Press (for the Francis A. Countway Library of Medicine).{{page needed|date=January 2015}} Tishler's interest in genetics arose from his laboratory research in the study of thyroid function in patients with phenylketonuria.
During the Vietnam War, Tishler worked as a Public Health Service officer at the National Institutes of Health. In the following years, he continued his basic laboratory work, but also was concerned with genetics and medicine in the terms of population and epidemiology. He was also involved in familial studies of hypertension at one of the first community health centers in the U.S., East Boston Neighborhood Health Center.
Selected publications
- {{cite journal | date = Mar 2005 | title = Linkage of serum leptin levels in families with sleep apnea | journal = Int J Obes (Lond) | volume = 29 | issue = 3| pages = 260–7 | doi=10.1038/sj.ijo.0802872| doi-access = free | last1 = Larkin | first1 = E. K. | last2 = Elston | first2 = R. C. | last3 = Patel | first3 = S. R. | last4 = Tishler | first4 = P. V. | last5 = Palmer | first5 = L. J. | last6 = Jenny | first6 = N. S. | last7 = Redline | first7 = S. | pmid = 15611783 }}
- {{cite journal | date = Jun 2004 | title = Whole genome scan for obstructive sleep apnea and obesity in African-American families | journal = Am J Respir Crit Care Med | volume = 169 | issue = 12| pages = 1314–21 | doi=10.1164/rccm.200304-493oc| last1 = Palmer | first1 = Lyle J. | last2 = Buxbaum | first2 = Sarah G. | last3 = Larkin | first3 = Emma K. | last4 = Patel | first4 = Sanjay R. | last5 = Elston | first5 = Robert C. | last6 = Tishler | first6 = Peter V. | last7 = Redline | first7 = Susan | pmid = 15070816 }}
- {{cite journal | date = May 2003 | title = Incidence of sleep-disordered breathing in an urban adult population: the relative importance of risk factors in the development of sleep-disordered breathing | journal = JAMA | volume = 289 | issue = 17| pages = 2230–7 | doi=10.1001/jama.289.17.2230 | pmid=12734134 | last1 = Tishler | first1 = PV | last2 = Larkin | first2 = EK | last3 = Schluchter | first3 = MD | last4 = Redline | first4 = S| doi-access = free }}
- {{cite journal | year = 1999 | title = The effect of therapeutic drugs and other pharmacologic agents on activity of porphobilinogen deaminase, the enzyme that is deficient in intermittent acute porphyria | journal = Life Sci | volume = 65 | issue = 2| pages = 207–1 | doi=10.1016/s0024-3205(99)00237-4| last1 = Tishler | first1 = Peter V. | pmid = 10416826 }}
- {{cite journal | date = Nov 1998 | title = Fetal alcohol effects in alcoholic veteran patients | journal = Alcohol Clin Exp Res | volume = 22 | issue = 8| pages = 1825–31 | doi=10.1111/j.1530-0277.1998.tb03988.x| last1 = Tishler | first1 = Peter V. | last2 = Henschel | first2 = Carroll E. | last3 = Ngo | first3 = Tu A. | last4 = Walters | first4 = Ellen E. | last5 = Worobec | first5 = Thomas G. | pmid = 9835303 }}
- {{cite journal | date = Aug 1992 | title = A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians | journal = JAMA | volume = 268 | issue = 7| pages = 877–81 | doi=10.1001/jama.1992.03490070059042| last1 = Stampfer | first1 = Meir J. | last2 = Malinow | first2 = M. R. | last3 = Willett | first3 = W. C. | last4 = Newcomer | first4 = L. M. | last5 = Upson | first5 = B. | last6 = Ullmann | first6 = D. | last7 = Tishler | first7 = P. V. | last8 = Hennekens | first8 = C. H. | pmid = 1640615 }}
- {{cite journal | date = Summer 1992 | title = "The care of the patient": a living testimony to Francis Weld Peabody | journal = Pharos Alpha Omega Alpha Honor Med Soc. | volume = 55 | issue = 3| pages = 32–6 | pmid = 1409858 | last1 = Tishler | first1 = P. V. }}
- {{cite journal | date = Oct 1990 | title = Thoughts as I watched the Peabody Building fall, March 31, 1990 | journal = N Engl J Med | volume = 323 | issue = 15| page = 1074 | doi=10.1056/nejm199010113231519| pmid = 2215573 | last1 = Tishler | first1 = P. V. }}
- {{cite journal | date = Oct 1979 | title = Healthy female carriers of a gene for the Alport syndrome: importance for genetic counseling | journal = Clin Genet | volume = 16 | issue = 4| pages = 291–4 | doi=10.1111/j.1399-0004.1979.tb01002.x| last1 = Tishler | first1 = Peter V. | pmid = 519898 | s2cid = 127230 }}
- {{cite journal | date = Sep 1975 | title = A family with coexistent von Recklinghausen's neurofibromatosis and von Hippel-Lindau's disease. Diseases possibly derived from a common gene | journal = Neurology | volume = 25 | issue = 9| pages = 840–4 | doi=10.1212/wnl.25.9.840| last1 = Tishler | first1 = P. V. | pmid = 808759 | s2cid = 24780531 }}
- {{cite journal | date = Feb 1969 | title = Phenylketonuria: therapeutic problems | journal = Br Med J | volume = 1 | issue = 5642| page = 510 | doi=10.1136/bmj.1.5642.510| pmc = 1982511 | last1 = Tishler | first1 = P. V. | pmid = 5764268 }}
- {{cite journal | date = May 1963 | title = Effect of thyroxine administered in vitro and in vivo on the succinoxidase and malic dehydrogenase reactions of frog myocardium | journal = Endocrinology | volume = 72 | pages = 673–6 | doi=10.1210/endo-72-5-673 | pmid=13985162 | last1 = Tishler | first1 = PV| issue = 5 }}
References
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External links
- [https://sleep.med.harvard.edu/people/faculty/157/Peter+V+Tishler+MD Peter Verveer Tishler] at Harvard University
- [http://www.porphyriafoundation.com/about-the-apf/scientific-advisory-board/dr-peter-tishler Peter Verveer Tishler] at the American Porphyria Foundation
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Category:American epidemiologists
Category:Harvard University alumni
Category:American medical historians
Category:21st-century American historians
Category:21st-century American male writers