Philip Eggleton
{{short description|British biochemist}}
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Philip Eggleton FRSE (19 March 1903 – 7 October 1954) was a British biochemist, physiologist, lecturer, and (with his wife Grace Palmer Eggleton), co-discoverer of Phosphagens.Selected Topics in the History of Biochemistry by G. Semenza
Life
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Eggleton was born at Kingston-on-Thames on 19 March 1903. He attended the Tiffin School there before going to the University of London graduating BSc in 1922 and receiving his doctorate (DSc) in 1930.
He then received a post at the University of Edinburgh rising to Reader in Biochemistry in the Physiology Department. He also acted as Scientific Advisor to BBC Scotland.
In 1927, in experiments on frog muscles in Cambridge, he discovered the release (on passing an electrical current) of a previously unknown substance which he labelled phosphagen.{{cite journal |last1=Eggleton|first1=Philip|last2=Eggleton|first2=Grace Palmer|date=7 July 1927|title=The Physiological Significance of Phosphagen|journal=The Journal of Physiology|volume=63|issue=2|pages=155–161|doi= 10.1113/jphysiol.1927.sp002391|pmid=16993876|pmc=1514923 }} It was shown that the substance played a major role in muscular contraction.{{cn|reason='https://www.cuchd.in/404.php' isn't a reliable source|date=September 2023}}
He was elected a Fellow of the Royal Society of Edinburgh in 1931. His proposers were Sir Edward Albert Sharpey-Schafer, Alfred Joseph Clark, and Henry Dryerre.
During the Second World War he served in the Gas Identification Service (part of the Edinburgh Civil Defence team).{{cite book|title=Biographical Index of Former Fellows of the Royal Society of Edinburgh 1783–2002|date=July 2006|publisher=The Royal Society of Edinburgh|isbn=0-902-198-84-X|url=https://www.royalsoced.org.uk/cms/files/fellows/biographical_index/fells_indexp1.pdf}}, page 296.
Family
He married Grace Palmer (1901-1970) who worked with him. The two discovered phosphagens.{{cn|date=October 2021}}
Publications
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- The Physiological Significance of Phosphagen (1927)
- Further Observations on Phosphagen (1928)
- A Problem in the Random Distribution of Particles (1944) with William Ogilvy Kermack
- The Use of Sodium Sulphate for the Preparation of Concentrated Protein-Free Tissue Extracts
References
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Category:British physiologists
Category:Fellows of the Royal Society of Edinburgh
Category:Academics of the University of Edinburgh
Category:People educated at Tiffin School
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