Platelet swirling

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| name = Platelet swirling

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| purpose = testing the quality of platelet-rich plasma

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Platelet swirling is a noninvasive method for testing the quality of platelet-rich plasma (PRP).{{cite journal |last1=Wagner |first1=S. J. |last2=Robinette |first2=D. |title=Evaluation of swirling, pH, and glucose tests for the detection of bacterial contamination in platelet concentrates |journal=Transfusion |date=November 1996 |volume=36 |issue=11–12 |pages=989–993 |doi=10.1046/j.1537-2995.1996.36111297091744.x |pmid=8937410 |s2cid=34296364 |url=https://pubmed.ncbi.nlm.nih.gov/8937410/ |access-date=28 November 2021 |issn=0041-1132}} Platelet swirling is caused by light diffraction due to the alignment of normal disc-shaped platelets. These discs align light that is diffracted, creating a cloud- or swirl-like appearance.{{cn|date=November 2021}}

Results of a platelet swirling test are recorded as positive or extensive swirl, moderate or intermediate swirl, and absent or negative swirl.{{cn|date=November 2021}}

References

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Further reading

  • {{cite journal |vauthors=Maurer-Spurej E, Chipperfield K |title=Past and future approaches to assess the quality of platelets for transfusion |journal=Transfusion Medicine Reviews |volume=21 |issue=4 |pages=295–306 |date=October 2007 |pmid=17900491 |doi=10.1016/j.tmrv.2007.05.005}}