Prince Francis Ernest of Hesse-Darmstadt

{{ infobox royalty

| name = Francis Ernest of Hesse-Darmstadt

| father = Ernest Louis, Landgrave of Hesse-Darmstadt

| mother = Dorothea Charlotte of Brandenburg-Ansbach

| birth_date = {{birth date|1695|1|25|df=yes}}

| birth_place = Gießen

| death_date = {{death date and age|1716|1|8|1695|1|25|df=yes}}

| death_place = Darmstadt

}}

Francis Ernest of Hesse-Darmstadt (born 25 January 1695 in Gießen; died: 8 January 1716 in Darmstadt) was a German nobleman.

He was the third son of Count Landgrave Ernest Louis of Hesse-Darmstadt (1667–1739) from his marriage to Dorothea Charlotte (1661–1705), daughter of the Margrave Albert of Brandenburg-Ansbach.{{cite book|title=Genealogie ascendante jusqu'au quatrieme degre inclusivement de tous les Rois et Princes de maisons souveraines de l'Europe actuellement vivans| trans-title=Genealogy up to the fourth degree inclusive of all the Kings and Princes of sovereign houses of Europe currently living |url=https://books.google.com/books?id=AINPAAAAcAAJ&pg=PA67|year=1768|publisher=Frederic Guillaume Birnstiel|location=Bourdeaux|language=fr|page=67}}

He replaced his brother Charles William of Hesse-Darmstadt as Colonel of the Hesse-Darmstadt Kreis Regiment when Charles William died during the War of Spanish Succession.