Progestin and adipoQ receptor

{{Short description|Group of receptors}}

The progestin and adipoQ receptor (PAQR) family is a group of receptors related to but distinct from the G protein-coupled receptor family, which have the similar seven transmembrane structure, but the N-terminal is located on the inner side of the cell.{{cite journal|last1=Tang|first1=Y. Tom|last2=Hu|first2=Tianhua|last3=Arterburn|first3=Matthew|last4=Boyle|first4=Bryan|last5=Bright|first5=Jessica M.|last6=Emtage|first6=Peter C.|last7=Funk|first7=Walter D.|title=PAQR Proteins: A Novel Membrane Receptor Family Defined by an Ancient7-Transmembrane Pass Motif|journal=Journal of Molecular Evolution|volume=61|issue=3|year=2005|pages=372–380|issn=0022-2844|doi=10.1007/s00239-004-0375-2|pmid=16044242}} It includes at least 11 receptors (PAQR1–PAQR11), including the adiponectin (adipoQ) receptors (AdipoRs), the membrane progesterone receptors (mPRs), and others.

In 2016, the University of Tokyo announced that it would launch an investigation into claims of fabrication of AdipoRs identification data, as accused by an anonymous person/group called Ordinary_researchers.[https://www.science.org/content/article/university-tokyo-investigate-data-manipulation-charges-against-six-prominent-research University of Tokyo to investigate data manipulation charges against six prominent research groups] ScienceInsider, Dennis Normile, Sep 20, 2016