Proliferating angioendotheliomatosis
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Proliferating Angioendotheliomatosis has historically been divided into two groups, (1) a reactive, involuting type and (2) a malignant, rapidly fatal type.James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. {{ISBN|0-7216-2921-0}}.{{rp|598}}
The reactive involuting type, reactive Angioendotheliomatosis is an rare cutaneous condition characterized histologically by a dense proliferation of small capillaries, and occurs in people with various diseases including subacute bacterial endocarditis and end-stage atherosclerotic disease. These people present with various skin lesions and rashes - most commonly on the thighs. Treatment aimed at the underlying condition hastens the resolution of the lesions.
The malignant type is an intravascular lymphoma, usually of the diffuse B-cell type, known as intravascular large B-cell lymphoma. It progresses rapidly through involvement of multiple body systems and mortality occurs in less than a year from the initial diagnosis. The average age of diagnosis being 55 years. The causative mechanism is unknown. In a few cases treatment with palliative chemotherapy has been effective.{{rp|598}}
Classification of Proliferating Angioendotheliomatosis
Proliferating angioendotheliomatosis may be divided into two types:{{cite book |author=Rapini, Ronald P. |author2=Bolognia, Jean L. |author3=Jorizzo, Joseph L. |title=Dermatology: 2-Volume Set |publisher=Mosby |location=St. Louis |year=2007 |isbn=978-1-4160-2999-1 }}
:* a reactive type – Reactive angioendotheliomatosis
:* a malignant type – Intravascular large B-cell lymphoma
Treatment
{{Empty section|date=November 2020}}In few cases palliative chemotherapy is effective.
A 30-year-old woman was diagnosed with cutaneous proliferating angioendotheliomatosis. She was treated with a local excision and radiotherapy.
See also
References
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External links
{{Medical resources
| ICD10 = {{ICD10|D|21||d|10}} or {{ICD10|C|83|3|c|81}}
| ICDO = {{ICDO|96803}}
}}
==External links==
{{Vascular tumors}}