Propizepine

{{Short description|Tricyclic antidepressant}}

{{Drugbox

| IUPAC_name = 6-(2-dimethylaminopropyl)-11H-pyrido[3,2-c][1,5]benzodiazepin-5-one

| image = Propizepine.png

| tradename = Depressin, Vagran

| pregnancy_category =

| legal_status = Rx-only

| routes_of_administration = Oral

| bioavailability =

| metabolism =

| elimination_half-life =

| excretion =

| CAS_number = 10321-12-7

| CAS_supplemental =
14559-79-6 (hydrochloride)

| ATC_prefix = none

| ATC_suffix =

| PubChem = 112029

| ChEMBL = 2104749

| ChemSpiderID = 100443

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = 09B57945V9

| C=17 | H=20 | N=4 | O=1

}}

Propizepine (brand names Depressin, Vagran) is a tricyclic antidepressant (TCA) used in France for the treatment of depression which was introduced in the 1970s.{{cite book | author = Swiss Pharmaceutical Society | title = Index Nominum 2000: International Drug Directory (Book with CD-ROM) | publisher = Medpharm Scientific Publishers | location = Boca Raton | year = 2000 | page = 888 | isbn = 3-88763-075-0 | url = https://books.google.com/books?id=5GpcTQD_L2oC&q=propizepine&pg=PA888}}{{cite book | first = David J. | last = Triggle | name-list-style = vanc | title = Dictionary of Pharmacological Agents | publisher = Chapman & Hall/CRC | location = Boca Raton | year = 1996 | page = 1680 | isbn = 0-412-46630-9 | url = https://books.google.com/books?id=A0THacd46ZsC&q=propizepine%20vagran&pg=PA1680}}{{cite book | vauthors = Muller NF, Dessing RP | work = European Society of Clinical Pharmacy | title = European Drug Index | volume = 33 | publisher = CRC Press | year = 1997 | page = 1339 | isbn = 3-7692-2114-1 | url = https://books.google.com/books?id=HiSdvzs2pPAC&q=propizepine&pg=PA1339}}{{cite journal | vauthors = Dereux JF | title = [Vagran 50: a situational antidepressant] | language = fr | journal = Semaine des Hopitaux. Therapeutique | volume = 52 | issue = 7–8 | pages = 385–8 | year = 1976 | pmid = 996559 }}

References

{{Reflist|2}}

{{Antidepressants}}

{{Navboxes

| title = Pharmacodynamics

| titlestyle = background:#ccccff

| list1 =

{{Adrenergic receptor modulators}}

{{Histamine receptor modulators}}

{{Monoamine reuptake inhibitors}}

{{Muscarinic acetylcholine receptor modulators}}

{{Serotonin receptor modulators}}

}}

{{Tricyclics}}

Category:Lactams

Category:Pyridobenzodiazepines

Category:Tricyclic antidepressants