Propylene glycol methyl ether acetate
{{Chembox
| Name =
| ImageFile = PGMEA.svg
| ImageSize =
| ImageFile1 = PGMEA chemical bottle.jpg
| ImageSize1 =
| PIN = 1-Methoxypropan-2-yl acetate
| OtherNames = PGMEA; 1-methoxy-2-propanyl acetate; PM Acetate; Propylene glycol monomethyl ether acetate
| SystematicName =
| Section1 = {{Chembox Identifiers
| CASNo_Ref = {{cascite|correct|CAS}}
| CASNo = 108-65-6
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = PA7O2U6S2Q
| PubChem = 7946
| ChemSpiderID = 7658
| SMILES = CC(COC)OC(=O)C
| InChI = 1/C6H12O3/c1-5(4-8-3)9-6(2)7/h5H,4H2,1-3H3
| InChIKey = LLHKCFNBLRBOGN-UHFFFAOYAD
| StdInChI = 1S/C6H12O3/c1-5(4-8-3)9-6(2)7/h5H,4H2,1-3H3
| StdInChIKey = LLHKCFNBLRBOGN-UHFFFAOYSA-N
}}
| Section2 = {{Chembox Properties
| C=6 | H=12 | O=3
| Appearance = Colorless liquid
| Density = 0.962 g/cm3
| MeltingPtC = -67
| BoilingPtC = 146
| Solubility = 23.0g /100mL H2O(25 °C
}}
| Section3 = {{Chembox Hazards
| MainHazards =
| HPhrases = {{H-phrases|226|402}}
| FlashPtC = 45
| ExploLimits = 1.5% - 7%
| AutoignitionPtC = 333
| AutoignitionPt_notes =
| NFPA-H = 1
| NFPA-F = 2
| NFPA-R = 0
| Section4 =
| Section5 =
| Section6 =
}}
Propylene glycol methyl ether acetate (PGMEA, 1-methoxy-2-propanol acetate) is a P-type glycol ether used in inks, coatings, and cleaners. It is sold by Dow Chemical under the name Dowanol PMA,{{Cite web | title=Search {{!}} Dow Inc. | url=http://www.dow.com/scripts/litorder.asp?filepath=oxysolvents/pdfs/noreg/110-00588.pdf | access-date=2025-04-06 | website=www.dow.com}} by Shell Chemical under the name methyl proxitol acetate,{{Cite web| url=http://s00.static-shell.com/content/dam/shell/static/chemicals/downloads/responsible-energy/methylproxitol-pgmemethylproxitolacetatepgmeaproductstewardships.pdf | title=Propylene glycol methyl ether (PGME) and Propylene glycol methyl ether acetate (PGMEA) [MethylPROXITOL and MethylPROXITOL acetate] - Product Stewardship Summary | accessdate=2014-08-01 | url-status=dead | archiveurl=https://web.archive.org/web/20140808050817/http://s00.static-shell.com/content/dam/shell/static/chemicals/downloads/responsible-energy/methylproxitol-pgmemethylproxitolacetatepgmeaproductstewardships.pdf | archivedate=2014-08-08}}{{cite web|url=https://www.shell.com/business-customers/chemicals/our-products/solvents-chemical/glycol-ethers.html |title=Shell Glycol Ethers and Acetates}} and by Eastman under the name PM Acetate.{{Cite web|url=https://www.eastman.com/Literature_Center/F/F346.pdf|title=Eastman EastaPure PM Acetate|last=|first=|date=23 September 2019|website=Eastman Chemical Company|archive-url=|archive-date=|accessdate=23 September 2019}}
In the semiconductor industry, PGMEA is a commonly used solvent, primarily for the application of surface adherents such as Bis(trimethylsilyl)amine (HMDS) on silicon wafers.{{cite web|url=https://www.microsi.com/product-category/lithography/adhesion-promoters/|title=HMDS primer (hexamethyldisilazane), DEATS and PGMEA|publisher=|access-date=2016-07-29|archive-date=2016-08-17|archive-url=https://web.archive.org/web/20160817013354/https://www.microsi.com/product-category/lithography/adhesion-promoters/|url-status=dead}} The compound is often the most abundant airborne, molecular contamination (AMC) in semiconductor cleanrooms,{{Cite web| url=http://www.balazs.com/file/otherelement/pj/1_amc_guidelines_rev2.34642.pdf | title=Airborne & Surface Molecular Contamination Guidelines | access-date=2016-07-29 | archive-url=https://web.archive.org/web/20161003181247/http://www.balazs.com/file/otherelement/pj/1_amc_guidelines_rev2.34642.pdf | archive-date=2016-10-03 | url-status=dead}} due to its evaporation into ambient air.