Protein BTG4
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Protein BTG4 also known as BTG family member 4 is a protein that in humans is encoded by the BTG4 gene (B-cell translocation gene 4).{{cite web | title = Entrez Gene: B-cell translocation gene 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54766}}{{cite journal |vauthors=Buanne P, Corrente G, Micheli L, Palena A, Lavia P, Spadafora C, Lakshmana MK, Rinaldi A, Banfi S, Quarto M, Bulfone A, Tirone F | title = Cloning of PC3B, a novel member of the PC3/BTG/TOB family of growth inhibitory genes, highly expressed in the olfactory epithelium | journal = Genomics | volume = 68 | issue = 3 | pages = 253–63 |date=September 2000 | pmid = 10995567 | doi = 10.1006/geno.2000.6288 }} BTG4 has anti-proliferative properties and can induce G1 cell cycle arrest.
References
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External links
- {{UCSC gene info|BTG4}}
Further reading
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- {{cite journal |vauthors=Auer RL, Starczynski J, McElwaine S |title=Identification of a potential role for POU2AF1 and BTG4 in the deletion of 11q23 in chronic lymphocytic leukemia. |journal=Genes Chromosomes Cancer |volume=43 |issue= 1 |pages= 1–10 |year= 2005 |pmid= 15672409 |doi= 10.1002/gcc.20159 |s2cid=34431756 |display-authors=etal}}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2002 |pmid= 12477932 |doi= 10.1073/pnas.242603899 |pmc=139241|bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }}
- {{cite journal |vauthors=Dong W, Tu S, Xie J |title=Frequent promoter hypermethylation and transcriptional downregulation of BTG4 gene in gastric cancer. |journal=Biochem. Biophys. Res. Commun. |volume=387 |issue= 1 |pages= 132–8 |year= 2009 |pmid= 19576178 |doi= 10.1016/j.bbrc.2009.06.140 |s2cid=5602860 |display-authors=etal}}
- {{cite journal |vauthors=Yoshida Y, Hosoda E, Nakamura T, Yamamoto T |title=Association of ANA, a member of the antiproliferative Tob family proteins, with a Caf1 component of the CCR4 transcriptional regulatory complex. |journal=Jpn. J. Cancer Res. |volume=92 |issue= 6 |pages= 592–6 |year= 2001 |pmid= 11429045 |pmc=5926753 |doi= 10.1111/j.1349-7006.2001.tb01135.x}}
- {{cite journal |vauthors=Toyota M, Suzuki H, Sasaki Y |title=Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. |journal=Cancer Res. |volume=68 |issue= 11 |pages= 4123–32 |year= 2008 |pmid= 18519671 |doi= 10.1158/0008-5472.CAN-08-0325 |display-authors=etal|doi-access=free }}
- {{cite journal |author=Tirone F |title=The gene PC3(TIS21/BTG2), prototype member of the PC3/BTG/TOB family: regulator in control of cell growth, differentiation, and DNA repair? |journal=J. Cell. Physiol. |volume=187 |issue= 2 |pages= 155–65 |year= 2001 |pmid= 11267995 |doi= 10.1002/jcp.1062 |s2cid=83558340 |doi-access=free }}
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