Protein SET

Protein SET has been shown to interact with:

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• Acidic leucine-rich nuclear phosphoprotein 32 family member A,{{cite journal | vauthors = Fan Z, Beresford PJ, Zhang D, Lieberman J | title = HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A | journal = Molecular and Cellular Biology | volume = 22 | issue = 8 | pages = 2810–20 | date = Apr 2002 | pmid = 11909973 | pmc = 133744 | doi = 10.1128/mcb.22.8.2810-2820.2002}}
• CDK5R1,{{cite journal | vauthors = Qu D, Li Q, Lim HY, Cheung NS, Li R, Wang JH, Qi RZ | title = The protein SET binds the neuronal Cdk5 activator p35nck5a and modulates Cdk5/p35nck5a activity | journal = The Journal of Biological Chemistry | volume = 277 | issue = 9 | pages = 7324–32 | date = Mar 2002 | pmid = 11741927 | doi = 10.1074/jbc.M107270200 | doi-access = free | hdl = 10536/DRO/DU:30101408 | hdl-access = free }}
• KLF5,{{cite journal | vauthors = Miyamoto S, Suzuki T, Muto S, Aizawa K, Kimura A, Mizuno Y, Nagino T, Imai Y, Adachi N, Horikoshi M, Nagai R | title = Positive and negative regulation of the cardiovascular transcription factor KLF5 by p300 and the oncogenic regulator SET through interaction and acetylation on the DNA-binding domain | journal = Molecular and Cellular Biology | volume = 23 | issue = 23 | pages = 8528–41 | date = Dec 2003 | pmid = 14612398 | pmc = 262669 | doi = 10.1128/mcb.23.23.8528-8541.2003}}
• NME1,{{cite journal | vauthors = Fan Z, Beresford PJ, Oh DY, Zhang D, Lieberman J | title = Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor | journal = Cell | volume = 112 | issue = 5 | pages = 659–72 | date = Mar 2003 | pmid = 12628186 | doi = 10.1016/s0092-8674(03)00150-8| s2cid = 14019153 | doi-access = free }} and
• TAF1A.{{cite journal | vauthors = Seo SB, McNamara P, Heo S, Turner A, Lane WS, Chakravarti D | title = Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein | journal = Cell | volume = 104 | issue = 1 | pages = 119–30 | date = Jan 2001 | pmid = 11163245 | doi = 10.1016/s0092-8674(01)00196-9| s2cid = 11144887 | doi-access = free }}

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{{Reflist}}

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• {{cite journal | vauthors = Nagata K, Kawase H, Handa H, Yano K, Yamasaki M, Ishimi Y, Okuda A, Kikuchi A, Matsumoto K | title = Replication factor encoded by a putative oncogene, set, associated with myeloid leukemogenesis | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 92 | issue = 10 | pages = 4279–83 | date = May 1995 | pmid = 7753797 | pmc = 41927 | doi = 10.1073/pnas.92.10.4279 | bibcode = 1995PNAS...92.4279N | doi-access = free }}
• {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1–2 | pages = 171–4 | date = Jan 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
• {{cite journal | vauthors = Adachi Y, Pavlakis GN, Copeland TD | title = Identification of in vivo phosphorylation sites of SET, a nuclear phosphoprotein encoded by the translocation breakpoint in acute undifferentiated leukemia | journal = FEBS Letters | volume = 340 | issue = 3 | pages = 231–5 | date = Mar 1994 | pmid = 8131851 | doi = 10.1016/0014-5793(94)80144-4 | s2cid = 36974869 | doi-access = free | bibcode = 1994FEBSL.340..231A }}
• {{cite journal | vauthors = Vaesen M, Barnikol-Watanabe S, Götz H, Awni LA, Cole T, Zimmermann B, Kratzin HD, Hilschmann N | title = Purification and characterization of two putative HLA class II associated proteins: PHAPI and PHAPII | journal = Biological Chemistry Hoppe-Seyler | volume = 375 | issue = 2 | pages = 113–26 | date = Feb 1994 | pmid = 8192856 | doi = 10.1515/bchm3.1994.375.2.113 }}
• {{cite journal | vauthors = Adachi Y, Pavlakis GN, Copeland TD | title = Identification and characterization of SET, a nuclear phosphoprotein encoded by the translocation break point in acute undifferentiated leukemia | journal = The Journal of Biological Chemistry | volume = 269 | issue = 3 | pages = 2258–62 | date = Jan 1994 | doi = 10.1016/S0021-9258(17)42162-4 | pmid = 8294483 | doi-access = free }}
• {{cite journal | vauthors = Adler HT, Nallaseth FS, Walter G, Tkachuk DC | title = HRX leukemic fusion proteins form a heterocomplex with the leukemia-associated protein SET and protein phosphatase 2A | journal = The Journal of Biological Chemistry | volume = 272 | issue = 45 | pages = 28407–14 | date = Nov 1997 | pmid = 9353299 | doi = 10.1074/jbc.272.45.28407 | doi-access = free }}
• {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1–2 | pages = 149–56 | date = Oct 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
• {{cite journal | vauthors = Carlson SG, Eng E, Kim EG, Perlman EJ, Copeland TD, Ballermann BJ | title = Expression of SET, an inhibitor of protein phosphatase 2A, in renal development and Wilms' tumor | journal = Journal of the American Society of Nephrology | volume = 9 | issue = 10 | pages = 1873–80 | date = Oct 1998 | doi = 10.1681/ASN.V9101873 | pmid = 9773788 | doi-access = free }}
• {{cite journal | vauthors = Brennan CM, Gallouzi IE, Steitz JA | title = Protein ligands to HuR modulate its interaction with target mRNAs in vivo | journal = The Journal of Cell Biology | volume = 151 | issue = 1 | pages = 1–14 | date = Oct 2000 | pmid = 11018049 | pmc = 2189805 | doi = 10.1083/jcb.151.1.1 }}
• {{cite journal | vauthors = Shikama N, Chan HM, Krstic-Demonacos M, Smith L, Lee CW, Cairns W, La Thangue NB | title = Functional interaction between nucleosome assembly proteins and p300/CREB-binding protein family coactivators | journal = Molecular and Cellular Biology | volume = 20 | issue = 23 | pages = 8933–43 | date = Dec 2000 | pmid = 11073993 | pmc = 86548 | doi = 10.1128/MCB.20.23.8933-8943.2000 }}
• {{cite journal | vauthors = Hartley JL, Temple GF, Brasch MA | title = DNA cloning using in vitro site-specific recombination | journal = Genome Research | volume = 10 | issue = 11 | pages = 1788–95 | date = Nov 2000 | pmid = 11076863 | pmc = 310948 | doi = 10.1101/gr.143000 }}
• {{cite journal | vauthors = Seo SB, McNamara P, Heo S, Turner A, Lane WS, Chakravarti D | title = Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein | journal = Cell | volume = 104 | issue = 1 | pages = 119–30 | date = Jan 2001 | pmid = 11163245 | doi = 10.1016/S0092-8674(01)00196-9 | s2cid = 11144887 | doi-access = free }}
• {{cite journal | vauthors = Minakuchi M, Kakazu N, Gorrin-Rivas MJ, Abe T, Copeland TD, Ueda K, Adachi Y | title = Identification and characterization of SEB, a novel protein that binds to the acute undifferentiated leukemia-associated protein SET | journal = European Journal of Biochemistry | volume = 268 | issue = 5 | pages = 1340–51 | date = Mar 2001 | pmid = 11231286 | doi = 10.1046/j.1432-1327.2001.02000.x | url = https://repository.kulib.kyoto-u.ac.jp/dspace/bitstream/2433/150179/1/yigak02406.pdf|doi-access=free | hdl = 2433/150179 }}
• {{cite journal | vauthors = Beresford PJ, Zhang D, Oh DY, Fan Z, Greer EL, Russo ML, Jaju M, Lieberman J | title = Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks | journal = The Journal of Biological Chemistry | volume = 276 | issue = 46 | pages = 43285–93 | date = Nov 2001 | pmid = 11555662 | doi = 10.1074/jbc.M108137200 | doi-access = free | url = http://nrs.harvard.edu/urn-3:HUL.InstRepos:41483403 }}
• {{cite journal | vauthors = Qu D, Li Q, Lim HY, Cheung NS, Li R, Wang JH, Qi RZ | title = The protein SET binds the neuronal Cdk5 activator p35nck5a and modulates Cdk5/p35nck5a activity | journal = The Journal of Biological Chemistry | volume = 277 | issue = 9 | pages = 7324–32 | date = Mar 2002 | pmid = 11741927 | doi = 10.1074/jbc.M107270200 | doi-access = free | hdl = 10536/DRO/DU:30101408 | hdl-access = free }}
• {{cite journal | vauthors = Fan Z, Beresford PJ, Zhang D, Lieberman J | title = HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A | journal = Molecular and Cellular Biology | volume = 22 | issue = 8 | pages = 2810–20 | date = Apr 2002 | pmid = 11909973 | pmc = 133744 | doi = 10.1128/MCB.22.8.2810-2820.2002 }}
• {{cite journal | vauthors = Cervoni N, Detich N, Seo SB, Chakravarti D, Szyf M | title = The oncoprotein Set/TAF-1beta, an inhibitor of histone acetyltransferase, inhibits active demethylation of DNA, integrating DNA methylation and transcriptional silencing | journal = The Journal of Biological Chemistry | volume = 277 | issue = 28 | pages = 25026–31 | date = Jul 2002 | pmid = 11978794 | doi = 10.1074/jbc.M202256200 | doi-access = free }}

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{{PDB Gallery|geneid=6418}}

Category:Histone Acetyltransferase Inhibitor

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