Prothionamide

{{Short description|Chemical compound}}

{{Drugbox

| Verifiedfields = changed

| Watchedfields = changed

| verifiedrevid = 447906208

| IUPAC_name = 2-propylpyridine-4-carbothioamide

| image = Protionamide.svg

| image2 = Prothionamide 3D ball.png

| tradename =

| Drugs.com = {{drugs.com|international|prothionamide}}

| pregnancy_AU =

| pregnancy_US =

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| legal_AU =

| legal_CA =

| legal_UK =

| legal_US =

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| routes_of_administration =

| bioavailability =

| protein_bound =

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| CAS_number_Ref = {{cascite|correct|??}}

| CAS_number = 14222-60-7

| ATC_prefix = J04

| ATC_suffix = AD01

| PubChem = 666418

| DrugBank_Ref = {{drugbankcite|correct|drugbank}}

| DrugBank = DB12667

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = 76YOO33643

| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}

| ChemSpiderID = 579891

| C=9 | H=12 | N=2 | S=1

| smiles = CCCc1cc(ccn1)C(=S)N

| StdInChI_Ref = {{stdinchicite|changed|chemspider}}

| StdInChI = 1S/C9H12N2S/c1-2-3-8-6-7(9(10)12)4-5-11-8/h4-6H,2-3H2,1H3,(H2,10,12)

| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}

| StdInChIKey = VRDIULHPQTYCLN-UHFFFAOYSA-N

}}

Protionamide (or prothionamide) is a drug used in the treatment of tuberculosis and leprosy.{{cite journal |vauthors=Wang F, Langley R, Gulten G, etal |title=Mechanism of thioamide drug action against tuberculosis and leprosy |journal=J. Exp. Med. |volume=204 |issue=1 |pages=73–8 |date=January 2007 |pmid=17227913 |pmc=2118422 |doi=10.1084/jem.20062100 |url=http://www.jem.org/cgi/pmidlookup?view=long&pmid=17227913}}{{cite journal |vauthors=Fajardo TT, Guinto RS, Cellona RV, Abalos RM, Dela Cruz EC, Gelber RH |title=A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy |journal=Am. J. Trop. Med. Hyg. |volume=74 |issue=3 |pages=457–61 |date=March 2006 |doi=10.4269/ajtmh.2006.74.457 |pmid=16525107 |s2cid=21415032 |url=http://www.ajtmh.org/cgi/pmidlookup?view=long&pmid=16525107|doi-access=free |url-access=subscription }}