Prurigo pigmentosa

{{Infobox medical condition (new)

| name = Prurigo pigmentosa

| synonyms =

| image =

| caption =

| pronounce =

| field =

| symptoms =

| complications =

| onset =

| duration =

| types =

| causes =

| risks =

| diagnosis =

| differential =

| prevention =

| treatment =

| medication =

| prognosis =

| frequency =

| deaths =

}}

Prurigo pigmentosa is a rare skin condition of unknown cause, characterized by the sudden onset of erythematous papules that leave a reticulated hyperpigmentation when they heal.{{cite book | vauthors = James WD, Berger T, Elston D |title=Andrews' Diseases of the Skin: Clinical Dermatology |date=2006 |publisher=Saunders Elsevier |location=Philadelphia |isbn=978-0-7216-2921-6 |edition=10th}}{{rp|57}} The condition has been associated with a strict ketogenic diet in case reports in the medical literature.{{cite journal | vauthors = Michaels JD, Hoss E, DiCaudo DJ, Price H | title = Prurigo pigmentosa after a strict ketogenic diet | journal = Pediatric Dermatology | volume = 32 | issue = 2 | pages = 248–251 | date = March 2015 | pmid = 24372546 | doi = 10.1111/pde.12275 | s2cid = 6607513 | doi-access = free }}{{Cite web|url=https://www.mdedge.com/dermatology/article/196684/pigmentation-disorders/prurigo-pigmentosa-induced-ketosis-resolution|title=Prurigo Pigmentosa Induced by Ketosis: Resolution Through Dietary Modification|website=www.mdedge.com|language=en|access-date=2019-10-14}} It was first reported by Masaharu Nagashima in 1978.{{cite journal | vauthors = Nagashima M | title = Prurigo pigmentosa--clinical observations of our 14 cases | journal = The Journal of Dermatology | volume = 5 | issue = 2 | pages = 61–67 | date = April 1978 | pmid = 353107 | doi = 10.1111/j.1346-8138.1978.tb01049.x | s2cid = 29199870 }} Research has shown that it may be caused by gut bacteria dysbiosis as a result of ketosis.{{cite journal | vauthors = Maco MW, Lee E, Wu Y, Lee R | title = Treatment of Prurigo Pigmentosa with Diet Modification: A Medical Case Study | journal = Hawai'i Journal of Medicine & Public Health | volume = 77 | issue = 5 | pages = 114–117 | date = May 2018 | pmid = 29761029 | pmc = 5945928 }}{{cite journal | vauthors = Ellis SR, Nguyen M, Vaughn AR, Notay M, Burney WA, Sandhu S, Sivamani RK | title = The Skin and Gut Microbiome and Its Role in Common Dermatologic Conditions | journal = Microorganisms | volume = 7 | issue = 11 | page = 550 | date = November 2019 | pmid = 31717915 | pmc = 6920876 | doi = 10.3390/microorganisms7110550 | doi-access = free }}