Pyrobaculum asR3 small RNA

{{Infobox rfam

| Name = xxx sRNA

| image = RF02793.svg

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| caption = Predicted secondary structure and sequence conservation of Pyrobaculum asRNA3

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| Rfam = RF02793

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| Tax_domain = Archaea

| GO = {{GO|0003729}}

| SO = {{SO|0000077}},{{SO|0000370}}

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asR3 is an archeal small RNA identified in seven Pyrobaculum species. The genus-specific nature can indicate this could be recent, stable adaptation.{{cite journal | vauthors = Bernick DL, Dennis PP, Lui LM, Lowe TM | title = Diversity of Antisense and Other Non-Coding RNAs in Archaea Revealed by Comparative Small RNA Sequencing in Four Pyrobaculum Species | journal = Frontiers in Microbiology | volume = 3 | pages = 231 | date = 2012 | pmid = 22783241 | pmc = 3388794 | doi = 10.3389/fmicb.2012.00231 | doi-access = free }} asR3 binds to the 3′-end of the tpi gene (triose-phosphate-isomerse).{{cite journal | vauthors = Alber T, Banner DW, Bloomer AC, Petsko GA, Phillips D, Rivers PS, Wilson IA | title = On the three-dimensional structure and catalytic mechanism of triose phosphate isomerase | journal = Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences | volume = 293 | issue = 1063 | pages = 159–171 | date = June 1981 | pmid = 6115415 | doi = 10.1098/rstb.1981.0069 | doi-access = }} The tpi mRNA has a conserved structural element located close to the stop codon. Binding of the asR3 may be able to compete against the formation of the tpi element structure and this may modulate the function of this highly conserved element.