Pyrrolidonyl-β-naphthylamide
{{chembox
| Verifiedfields = changed
| verifiedrevid = 464377852
| ImageFile=Pyrrolidonyl-β-naphthylamide.svg
| ImageSize=200px
| IUPACName=N1-(Naphthalen-2-yl)-5-oxo-L-prolinamide
| SystematicName=(2S)-N-(Naphthalen-2-yl)-5-oxopyrrolidine-2-carboxamide
| OtherNames=Pyrrolidonyl-beta-naphthylamide
|Section1={{Chembox Identifiers
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 81932
| InChI = 1/C15H14N2O2/c18-14-8-7-13(17-14)15(19)16-12-6-5-10-3-1-2-4-11(10)9-12/h1-6,9,13H,7-8H2,(H,16,19)(H,17,18)
| InChIKey = BZEPQNMASTUAMY-UHFFFAOYAS
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C15H14N2O2/c18-14-8-7-13(17-14)15(19)16-12-6-5-10-3-1-2-4-11(10)9-12/h1-6,9,13H,7-8H2,(H,16,19)(H,17,18)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = BZEPQNMASTUAMY-UHFFFAOYSA-N
| CASNo_Ref = {{cascite|changed|??}}
| CASNo=22155-91-5
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 6G5U8A2YEH
| PubChem=90745
| SMILES = O=C(Nc2cc1ccccc1cc2)C3NC(=O)CC3
}}
|Section2={{Chembox Properties
| C=15 | H=14 | N=2 | O=2
| Appearance=
| Density=
| MeltingPt=
| BoilingPt=
| Solubility=
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|Section3={{Chembox Hazards
| MainHazards=
| FlashPt=
| AutoignitionPt =
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Pyrrolidonyl-β-naphthylamide (PYR) is a molecule used in microbiology to detect the presence of pyrrolidonyl peptidase.{{Cite journal | doi = 10.1016/0732-8893(86)90055-6| title = Value of the l-pyrrolidonyl-β-naphthylamide hydrolysis test for identification of select gram-positive cocci| journal = Diagnostic Microbiology and Infectious Disease| volume = 4| pages = 43–47| year = 1986| last1 = Oberhofer| first1 = Thomas R.}} In the presence of bacteria with pyrrolidonyl peptidase, it is broken down to pyroglutamic acid and 2-naphthylamine. To detect this process, p-dimethylaminocinnamaldehyde is added and a change to a pink color can then be detected.
References
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{{Clinical microbiology techniques}}
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