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RAB9A

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{{Short description|Protein-coding gene in the species Homo sapiens}}

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Ras-related protein Rab-9A is a protein that in humans is encoded by the RAB9A gene.{{cite journal | vauthors = Davies JP, Cotter PD, Ioannou YA | title = Cloning and mapping of human Rab7 and Rab9 cDNA sequences and identification of a Rab9 pseudogene | journal = Genomics | volume = 41 | issue = 1 | pages = 131–4 | date = May 1997 | pmid = 9126495 | doi = 10.1006/geno.1997.4644 }}{{cite web | title = Entrez Gene: RAB9A RAB9A, member RAS oncogene family| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9367}}

Interactions

RAB9A has been shown to interact with RABEPK,{{cite journal | vauthors = Díaz E, Schimmöller F, Pfeffer SR | title = A novel Rab9 effector required for endosome-to-TGN transport | journal = J. Cell Biol. | volume = 138 | issue = 2 | pages = 283–90 | date = July 1997 | pmid = 9230071 | pmc = 2138197 | doi = 10.1083/jcb.138.2.283 }} TIP47{{cite journal | vauthors = Carroll KS, Hanna J, Simon I, Krise J, Barbero P, Pfeffer SR | title = Role of Rab9 GTPase in facilitating receptor recruitment by TIP47 | journal = Science | volume = 292 | issue = 5520 | pages = 1373–6 | date = May 2001 | pmid = 11359012 | doi = 10.1126/science.1056791 | bibcode = 2001Sci...292.1373C | s2cid = 31343936 }} and the Biogenesis of lysosome-related organelles complex 3.{{cite journal | vauthors = Kloer DP, Rojas R, Ivan V, Moriyama K, van Vlijmen T, Murthy N, Ghirlando R, van der Sluijs P, Hurley JH, Bonifacino JS | title = Assembly of the biogenesis of lysosome-related organelles complex-3 (BLOC-3) and its interaction with Rab9 | journal = J. Biol. Chem. | volume = 285 | issue = 10 | pages = 7794–7804 |date = March 2010 | pmid = 20048159 | pmc = 2844223 | doi =10.1074/jbc.M109.069088 | doi-access = free }}

References

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Further reading

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  • {{cite journal | vauthors = Shapiro AD, Pfeffer SR | title = Quantitative analysis of the interactions between prenyl Rab9, GDP dissociation inhibitor-alpha, and guanine nucleotides | journal = J. Biol. Chem. | volume = 270 | issue = 19 | pages = 11085–90 | year = 1995 | pmid = 7744738 | doi = 10.1074/jbc.270.19.11085 |doi-access= free}}
  • {{cite journal | vauthors = Soldati T, Riederer MA, Pfeffer SR | title = Rab GDI: a solubilizing and recycling factor for rab9 protein | journal = Mol. Biol. Cell | volume = 4 | issue = 4 | pages = 425–34 | year = 1993 | pmid = 8389620 | pmc = 300943 | doi = 10.1091/mbc.4.4.425 }}
  • {{cite journal | vauthors = Díaz E, Schimmöller F, Pfeffer SR | title = A novel Rab9 effector required for endosome-to-TGN transport | journal = J. Cell Biol. | volume = 138 | issue = 2 | pages = 283–90 | year = 1997 | pmid = 9230071 | pmc = 2138197 | doi = 10.1083/jcb.138.2.283 }}
  • {{cite journal | vauthors = de Leeuw HP, Koster PM, Calafat J, Janssen H, van Zonneveld AJ, van Mourik JA, Voorberg J | title = Small GTP-binding proteins in human endothelial cells | journal = Br. J. Haematol. | volume = 103 | issue = 1 | pages = 15–9 | year = 1998 | pmid = 9792283 | doi = 10.1046/j.1365-2141.1998.00965.x | s2cid = 24857520 | doi-access = free }}
  • {{cite journal | vauthors = Shisheva A, Chinni SR, DeMarco C | title = General role of GDP dissociation inhibitor 2 in membrane release of Rab proteins: modulations of its functional interactions by in vitro and in vivo structural modifications | journal = Biochemistry | volume = 38 | issue = 36 | pages = 11711–21 | year = 1999 | pmid = 10512627 | doi = 10.1021/bi990200r }}
  • {{cite journal | vauthors = Carroll KS, Hanna J, Simon I, Krise J, Barbero P, Pfeffer SR | title = Role of Rab9 GTPase in facilitating receptor recruitment by TIP47 | journal = Science | volume = 292 | issue = 5520 | pages = 1373–6 | year = 2001 | pmid = 11359012 | doi = 10.1126/science.1056791 | bibcode = 2001Sci...292.1373C | s2cid = 31343936 }}
  • {{cite journal | vauthors = Orzaez D, de Jong AJ, Woltering EJ | title = A tomato homologue of the human protein PIRIN is induced during programmed cell death | journal = Plant Mol. Biol. | volume = 46 | issue = 4 | pages = 459–68 | year = 2001 | pmid = 11485202 | doi = 10.1023/A:1010618515051 | s2cid = 8587440 }}
  • {{cite journal | vauthors = Michel F, Soler-Lopez M, Petosa C, Cramer P, Siebenlist U, Müller CW | title = Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family | journal = EMBO J. | volume = 20 | issue = 22 | pages = 6180–90 | year = 2002 | pmid = 11707390 | pmc = 125740 | doi = 10.1093/emboj/20.22.6180 }}
  • {{cite journal | vauthors = Barbero P, Bittova L, Pfeffer SR | title = Visualization of Rab9-mediated vesicle transport from endosomes to the trans-Golgi in living cells | journal = J. Cell Biol. | volume = 156 | issue = 3 | pages = 511–8 | year = 2002 | pmid = 11827983 | pmc = 2173336 | doi = 10.1083/jcb.200109030 }}
  • {{cite journal | vauthors = Hanna J, Carroll K, Pfeffer SR | title = Identification of residues in TIP47 essential for Rab9 binding | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 99 | issue = 11 | pages = 7450–4 | year = 2002 | pmid = 12032303 | pmc = 124251 | doi = 10.1073/pnas.112198799 | bibcode = 2002PNAS...99.7450H | doi-access = free }}
  • {{cite journal | vauthors = Walter M, Davies JP, Ioannou YA | title = Telomerase immortalization upregulates Rab9 expression and restores LDL cholesterol egress from Niemann-Pick C1 late endosomes | journal = J. Lipid Res. | volume = 44 | issue = 2 | pages = 243–53 | year = 2004 | pmid = 12576506 | doi = 10.1194/jlr.M200230-JLR200 | doi-access = free }}
  • {{cite journal | vauthors = Seaman MN | title = Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer | journal = J. Cell Biol. | volume = 165 | issue = 1 | pages = 111–22 | year = 2004 | pmid = 15078902 | pmc = 2172078 | doi = 10.1083/jcb.200312034 }}
  • {{cite journal | vauthors = Chen L, DiGiammarino E, Zhou XE, Wang Y, Toh D, Hodge TW, Meehan EJ | title = High resolution crystal structure of human Rab9 GTPase: a novel antiviral drug target | journal = J. Biol. Chem. | volume = 279 | issue = 38 | pages = 40204–8 | year = 2004 | pmid = 15263003 | doi = 10.1074/jbc.M407114200 | doi-access = free}}
  • {{cite journal | vauthors = Ganley IG, Carroll K, Bittova L, Pfeffer S | title = Rab9 GTPase regulates late endosome size and requires effector interaction for its stability | journal = Mol. Biol. Cell | volume = 15 | issue = 12 | pages = 5420–30 | year = 2005 | pmid = 15456905 | pmc = 532021 | doi = 10.1091/mbc.E04-08-0747 }}
  • {{cite journal | vauthors = Ganley IG, Pfeffer SR | title = Cholesterol accumulation sequesters Rab9 and disrupts late endosome function in NPC1-deficient cells | journal = J. Biol. Chem. | volume = 281 | issue = 26 | pages = 17890–9 | year = 2006 | pmid = 16644737 | pmc = 3650718 | doi = 10.1074/jbc.M601679200 | doi-access = free }}
  • {{cite journal | vauthors = Aivazian D, Serrano RL, Pfeffer S | title = TIP47 is a key effector for Rab9 localization | journal = J. Cell Biol. | volume = 173 | issue = 6 | pages = 917–26 | year = 2006 | pmid = 16769818 | pmc = 2063917 | doi = 10.1083/jcb.200510010 }}

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