RNF4

RNF4 has been shown to interact with TCF20,{{cite journal | vauthors = Lyngsø C, Bouteiller G, Damgaard CK, Ryom D, Sanchez-Muñoz S, Nørby PL, Bonven BJ, Jørgensen P | title = Interaction between the transcription factor SPBP and the positive cofactor RNF4. An interplay between protein binding zinc fingers | journal = The Journal of Biological Chemistry | volume = 275 | issue = 34 | pages = 26144–9 | date = Aug 2000 | pmid = 10849425 | doi = 10.1074/jbc.M003405200 | doi-access = free }} PATZ1{{cite journal | vauthors = Fedele M, Benvenuto G, Pero R, Majello B, Battista S, Lembo F, Vollono E, Day PM, Santoro M, Lania L, Bruni CB, Fusco A, Chiariotti L | title = A novel member of the BTB/POZ family, PATZ, associates with the RNF4 RING finger protein and acts as a transcriptional repressor | journal = The Journal of Biological Chemistry | volume = 275 | issue = 11 | pages = 7894–901 | date = Mar 2000 | pmid = 10713105 | doi = 10.1074/jbc.275.11.7894 | doi-access = free }}{{cite journal | vauthors = Pero R, Lembo F, Palmieri EA, Vitiello C, Fedele M, Fusco A, Bruni CB, Chiariotti L | title = PATZ attenuates the RNF4-mediated enhancement of androgen receptor-dependent transcription | journal = The Journal of Biological Chemistry | volume = 277 | issue = 5 | pages = 3280–5 | date = Feb 2002 | pmid = 11719514 | doi = 10.1074/jbc.M109491200 | doi-access = free }} and Androgen receptor.{{cite journal | vauthors = Moilanen AM, Poukka H, Karvonen U, Häkli M, Jänne OA, Palvimo JJ | title = Identification of a novel RING finger protein as a coregulator in steroid receptor-mediated gene transcription | journal = Molecular and Cellular Biology | volume = 18 | issue = 9 | pages = 5128–39 | date = Sep 1998 | pmid = 9710597 | pmc = 109098 | doi=10.1128/mcb.18.9.5128}}{{cite journal | vauthors = Poukka H, Aarnisalo P, Santti H, Jänne OA, Palvimo JJ | title = Coregulator small nuclear RING finger protein (SNURF) enhances Sp1- and steroid receptor-mediated transcription by different mechanisms | journal = The Journal of Biological Chemistry | volume = 275 | issue = 1 | pages = 571–9 | date = Jan 2000 | pmid = 10617653 | doi = 10.1074/jbc.275.1.571 | doi-access = free }} RNF4 has been shown to be responsible for the degradation of the Werner syndrome helicase in MSI-H cells after WRN inhibition.{{cite journal | date = July 2024 |vauthors=Rodríguez Pérez F, Natwick D, Schiff L, McSwiggen D, Heckert A, Huey M, Morrison H, Loo M, Miranda RG, Filbin J, Ortega J, Van Buren K, Murnock D, Tao A, Butler R, Cheng K, Tarvestad W, Zhang Z, Gonzalez E, Miller RM, Kelly M, Tang Y, Ho J, Anderson D, Bashore C, Basham S | title = WRN inhibition leads to its chromatin-associated degradation via the PIAS4-RNF4-p97/VCP axis | journal = Nat. Commun. | volume = 15 | issue = 6059 | pmid = 39025847| pmc=11258360 | doi = 10.1038/s41467-024-50178-3| doi-access = free}}

• RING finger domain

{{Reflist}}

{{refbegin | 2}}

• {{cite journal | vauthors = Moilanen AM, Poukka H, Karvonen U, Häkli M, Jänne OA, Palvimo JJ | title = Identification of a novel RING finger protein as a coregulator in steroid receptor-mediated gene transcription | journal = Molecular and Cellular Biology | volume = 18 | issue = 9 | pages = 5128–39 | date = Sep 1998 | pmid = 9710597 | pmc = 109098 | doi = 10.1128/mcb.18.9.5128}}
• {{cite journal | vauthors = Hadano S, Ishida Y, Ikeda JE | title = The primary structure and genomic organization of five novel transcripts located close to the Huntington's disease gene on human chromosome 4p16.3 | journal = DNA Research | volume = 5 | issue = 3 | pages = 177–86 | date = Jun 1998 | pmid = 9734812 | doi = 10.1093/dnares/5.3.177 | doi-access = free }}
• {{cite journal | vauthors = Poukka H, Aarnisalo P, Santti H, Jänne OA, Palvimo JJ | title = Coregulator small nuclear RING finger protein (SNURF) enhances Sp1- and steroid receptor-mediated transcription by different mechanisms | journal = The Journal of Biological Chemistry | volume = 275 | issue = 1 | pages = 571–9 | date = Jan 2000 | pmid = 10617653 | doi = 10.1074/jbc.275.1.571 | doi-access = free }}
• {{cite journal | vauthors = Fedele M, Benvenuto G, Pero R, Majello B, Battista S, Lembo F, Vollono E, Day PM, Santoro M, Lania L, Bruni CB, Fusco A, Chiariotti L | title = A novel member of the BTB/POZ family, PATZ, associates with the RNF4 RING finger protein and acts as a transcriptional repressor | journal = The Journal of Biological Chemistry | volume = 275 | issue = 11 | pages = 7894–901 | date = Mar 2000 | pmid = 10713105 | doi = 10.1074/jbc.275.11.7894 | doi-access = free }}
• {{cite journal | vauthors = Galili N, Nayak S, Epstein JA, Buck CA | title = Rnf4, a RING protein expressed in the developing nervous and reproductive systems, interacts with Gscl, a gene within the DiGeorge critical region | journal = Developmental Dynamics | volume = 218 | issue = 1 | pages = 102–11 | date = May 2000 | pmid = 10822263 | doi = 10.1002/(SICI)1097-0177(200005)218:1<102::AID-DVDY9>3.0.CO;2-A | doi-access = free }}
• {{cite journal | vauthors = Lyngsø C, Bouteiller G, Damgaard CK, Ryom D, Sanchez-Muñoz S, Nørby PL, Bonven BJ, Jørgensen P | title = Interaction between the transcription factor SPBP and the positive cofactor RNF4. An interplay between protein binding zinc fingers | journal = The Journal of Biological Chemistry | volume = 275 | issue = 34 | pages = 26144–9 | date = Aug 2000 | pmid = 10849425 | doi = 10.1074/jbc.M003405200 | doi-access = free }}
• {{cite journal | vauthors = Häkli M, Karvonen U, Jänne OA, Palvimo JJ | title = The RING finger protein SNURF is a bifunctional protein possessing DNA binding activity | journal = The Journal of Biological Chemistry | volume = 276 | issue = 26 | pages = 23653–60 | date = Jun 2001 | pmid = 11319220 | doi = 10.1074/jbc.M009891200 | doi-access = free }}
• {{cite journal | vauthors = Saville B, Poukka H, Wormke M, Janne OA, Palvimo JJ, Stoner M, Samudio I, Safe S | title = Cooperative coactivation of estrogen receptor alpha in ZR-75 human breast cancer cells by SNURF and TATA-binding protein | journal = The Journal of Biological Chemistry | volume = 277 | issue = 4 | pages = 2485–97 | date = Jan 2002 | pmid = 11696545 | doi = 10.1074/jbc.M109021200 | doi-access = free }}
• {{cite journal | vauthors = Pero R, Lembo F, Palmieri EA, Vitiello C, Fedele M, Fusco A, Bruni CB, Chiariotti L | title = PATZ attenuates the RNF4-mediated enhancement of androgen receptor-dependent transcription | journal = The Journal of Biological Chemistry | volume = 277 | issue = 5 | pages = 3280–5 | date = Feb 2002 | pmid = 11719514 | doi = 10.1074/jbc.M109491200 | doi-access = free }}
• {{cite journal | vauthors = Yan W, Hirvonen-Santti SJ, Palvimo JJ, Toppari J, Jänne OA | title = Expression of the nuclear RING finger protein SNURF/RNF4 during rat testis development suggests a role in spermatid maturation | journal = Mechanisms of Development | volume = 118 | issue = 1–2 | pages = 247–53 | date = Oct 2002 | pmid = 12351196 | doi = 10.1016/S0925-4773(02)00261-7 | s2cid = 15579434 | doi-access = free }}
• {{cite journal | vauthors = Pero R, Lembo F, Chieffi P, Del Pozzo G, Fedele M, Fusco A, Bruni CB, Chiariotti L | title = Translational regulation of a novel testis-specific RNF4 transcript | journal = Molecular Reproduction and Development | volume = 66 | issue = 1 | pages = 1–7 | date = Sep 2003 | pmid = 12874792 | doi = 10.1002/mrd.10322 | s2cid = 6206480 }}
• {{cite journal | vauthors = Kaiser FJ, Möröy T, Chang GT, Horsthemke B, Lüdecke HJ | title = The RING finger protein RNF4, a co-regulator of transcription, interacts with the TRPS1 transcription factor | journal = The Journal of Biological Chemistry | volume = 278 | issue = 40 | pages = 38780–5 | date = Oct 2003 | pmid = 12885770 | doi = 10.1074/jbc.M306259200 | doi-access = free }}
• {{cite journal | vauthors = Lin DY, Fang HI, Ma AH, Huang YS, Pu YS, Jenster G, Kung HJ, Shih HM | title = Negative modulation of androgen receptor transcriptional activity by Daxx | journal = Molecular and Cellular Biology | volume = 24 | issue = 24 | pages = 10529–41 | date = Dec 2004 | pmid = 15572661 | pmc = 533990 | doi = 10.1128/MCB.24.24.10529-10541.2004 }}

{{refend}}

• {{MeshName|RNF4+protein,+human}}

{{Protein-stub}}

Category:RING finger proteins