RNGTT
{{Short description|Protein-coding gene in the species Homo sapiens}}
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mRNA-capping enzyme is a protein that in humans is encoded by the RNGTT gene.{{cite journal |vauthors=Pillutla RC, Shimamoto A, Furuichi Y, Shatkin AJ | title = Human mRNA capping enzyme (RNGTT) and cap methyltransferase (RNMT) map to 6q16 and 18p11.22-p11.23, respectively | journal = Genomics | volume = 54 | issue = 2 | pages = 351–3 |date=Jan 1999 | pmid = 9828141 | doi = 10.1006/geno.1998.5604 }}{{cite journal |vauthors=Yamada-Okabe T, Doi R, Shimmi O, Arisawa M, Yamada-Okabe H | title = Isolation and characterization of a human cDNA for mRNA 5'-capping enzyme | journal = Nucleic Acids Res | volume = 26 | issue = 7 | pages = 1700–6 |date=May 1998 | pmid = 9512541 | pmc = 147440 | doi =10.1093/nar/26.7.1700 }}{{cite web | title = Entrez Gene: RNGTT RNA guanylyltransferase and 5'-phosphatase| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8732}}
References
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Further reading
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- {{cite journal | author=Yue Z |title=Mammalian capping enzyme complements mutant Saccharomyces cerevisiae lacking mRNA guanylyltransferase and selectively binds the elongating form of RNA polymerase II |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 24 |pages= 12898–903 |year= 1998 |pmid= 9371772 |doi=10.1073/pnas.94.24.12898 | pmc=24235 | author2=Maldonado E | author3=Pillutla R | last4=Cho | first4=H | last5=Reinberg | first5=D | last6=Shatkin | first6=AJ |doi-access=free }}
- {{cite journal | author=Tsukamoto T |title=Cloning and characterization of two human cDNAs encoding the mRNA capping enzyme |journal=Biochem. Biophys. Res. Commun. |volume=243 |issue= 1 |pages= 101–8 |year= 1998 |pmid= 9473487 |doi= 10.1006/bbrc.1997.8038 | author2=Shibagaki Y | author3=Murakoshi T | last4=Suzuki | first4=Masako | last5=Nakamura | first5=Akiko | last6=Gotoh | first6=Hideo | last7=Mizumoto | first7=Kiyohisa }}
- {{cite journal |vauthors=Pillutla RC, Yue Z, Maldonado E, Shatkin AJ |title=Recombinant human mRNA cap methyltransferase binds capping enzyme/RNA polymerase IIo complexes |journal=J. Biol. Chem. |volume=273 |issue= 34 |pages= 21443–6 |year= 1998 |pmid= 9705270 |doi=10.1074/jbc.273.34.21443 |doi-access= free}}
- {{cite journal |vauthors=Wen Y, Shatkin AJ |title=Transcription elongation factor hSPT5 stimulates mRNA capping |journal=Genes Dev. |volume=13 |issue= 14 |pages= 1774–9 |year= 1999 |pmid= 10421630 |doi=10.1101/gad.13.14.1774 | pmc=316881 }}
- {{cite journal | author=Chiu YL |title=HIV-1 Tat protein interacts with mammalian capping enzyme and stimulates capping of TAR RNA |journal=J. Biol. Chem. |volume=276 |issue= 16 |pages= 12959–66 |year= 2001 |pmid= 11278368 |doi= 10.1074/jbc.M007901200 | author2=Coronel E | author3=Ho CK | last4=Shuman | first4=S | last5=Rana | first5=TM |doi-access=free }}
- {{cite journal | author=Chiu YL |title=Tat stimulates cotranscriptional capping of HIV mRNA |journal=Mol. Cell |volume=10 |issue= 3 |pages= 585–97 |year= 2002 |pmid= 12408826 |doi=10.1016/S1097-2765(02)00630-5 | author2=Ho CK | author3=Saha N | last4=Schwer | first4=Beate | last5=Shuman | first5=Stewart | last6=Rana | first6=Tariq M | doi-access=free }}
- {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 | author2=Feingold EA | author3=Grouse LH | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal | author=Zhou M |title=The Tat/TAR-dependent phosphorylation of RNA polymerase II C-terminal domain stimulates cotranscriptional capping of HIV-1 mRNA |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 22 |pages= 12666–71 |year= 2004 |pmid= 14569024 |doi= 10.1073/pnas.1835726100 | pmc=240675 | author2=Deng L | author3=Kashanchi F | last4=Brady | first4=JN | last5=Shatkin | first5=AJ | last6=Kumar | first6=A |doi-access=free }}
- {{cite journal | author=Suzuki Y |title=Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604 | pmc=515316 | author2=Yamashita R | author3=Shirota M | last4=Sakakibara | first4=Y | last5=Chiba | first5=J | last6=Mizushima-Sugano | first6=J | last7=Nakai | first7=K | last8=Sugano | first8=S }}
- {{cite journal | author=Olsen JV |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 | author2=Blagoev B | author3=Gnad F | last4=Macek | first4=Boris | last5=Kumar | first5=Chanchal | last6=Mortensen | first6=Peter | last7=Mann | first7=Matthias |s2cid=7827573 | doi-access=free}}
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External links
- [https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/O60942 PDBe-KB] provides an overview of all the structure information available in the PDB for Human mRNA-capping enzyme (RNGTT)
{{PDB Gallery|geneid=8732}}
{{Protein tyrosine phosphatases}}
{{gene-6-stub}}