Rabbit vesivirus

{{Short description|Caliciviridae virus}}

{{Italic title}}

Rabbit vesivirus (RaV) is a Caliciviridae virus that was first isolated in the Veterinary Diagnostic Laboratory at Oregon State University, from the feces of rabbits suffering from gastrointestinal disease. The virus is a non-enveloped, isometric virus with diameter of around 30 nanometer.

Its viral genome is 8,295 nucleotides in size, consisting of positive single-stranded RNA with a small protein (VPg) covalently linked to its 5′ terminus and a 3′ poly-A tail with an average length of 85 nucleotides. The genome comprises three open reading frames, the most 5′ of which encodes a 1,880 amino acid proteolysis that yields the non-structural polypeptides upon self-cleavage. The vesivirus is the only genus of which all members are cultivable.{{Cite journal |last1=Álvarez |first1=Ángel L. |last2=García-Manso |first2=Alberto |last3=Dalton |first3=Kevin P. |last4=Martín-Alonso |first4=José M. |last5=Nicieza |first5=Inés |last6=Podadera |first6=Ana |last7=Acosta-Zaldívar |first7=Maikel |last8=de Llano |first8=Daniel |last9=Parra |first9=Francisco |date=2020 |title=Reverse Genetics System for Rabbit vesivirus |journal=Frontiers in Microbiology |volume=11 |doi=10.3389/fmicb.2020.596245 |issn=1664-302X |doi-access=free |pmid=33304341 |pmc=7693663 }}{{Creative Commons text attribution notice|cc=by4|from this source=yes}}