Ray Iles
{{short description|Biomedical scientist}}
Ray Kruse Iles is a biomedical scientist who was head of the Williamson Laboratory for Molecular Oncology at St Bartholomew's Hospital in London.{{Cite book|url=https://books.google.com/books?id=kqjODwAAQBAJ&q=Williamson+Laboratory+St+Bartholomews&pg=PA73|title=100 Years of Human Chorionic Gonadotropin: Reviews and New Perspectives|isbn=9780128200506|last1=Cole|first1=Laurence A.|last2=Butler|first2=Stephen A.|date=17 February 2020|publisher=Elsevier }}
Career
Iles has a particular interest in the interface between rational processing, emotional motivation and endocrinology.{{Cite web|url=https://www.researchgate.net/profile/Ray_Iles|title=Ray Kruse Iles {{!}} BSc MSc PhD CBiol FRSB FRSC {{!}} College of Health Sciences|website=ResearchGate|language=en|access-date=2019-09-16}}
He co-founded the ELK-Health Foundation, with psychotherapist Tadhg Ó Séaghdha, in 2004. The ELK-Foundation Health (named after Iles's father, Eric Leonard Kruse) is now the National Institutes for Stress, Anxiety and Depression (NISAD), centred in Lund, Sweden. It still uses the ELK-Health name in its programmes and clinics, which support people needing to change habits that harm their physical and emotional health.
Iles's interest in women's and reproduction health led him, in 2011, to become the founding director of the biomarker diagnostic company MAPSciences.{{Cite web|url=https://mapsciences.com/team/|title = MAP Sciences | Team}}
Iles is the inventor of new diagnostic technology, six clinical screening tests for pregnancy disorders and Down syndrome/prenatal diagnosis,{{cite patent|title=Urinary screening for down syndrome and other aneuploidies|country=US|number=6025149|issue-date=February 15, 2000|inventor-last=Cuckle|inventor2-last=GB|inventor3-last=GB|inventor-first=Howard S.|inventor3-first=Raymond K.}}{{Cite web|url=https://worldwide.espacenet.com/publicationDetails/biblio?CC=WO&NR=9703363A1&KC=A1&FT=D|title=Espacenet - Bibliographic data|website=worldwide.espacenet.com|access-date=2019-02-28}}{{Cite web|url=https://worldwide.espacenet.com/publicationDetails/biblio?CC=US&NR=2017242023A1&KC=A1&FT=D|title=Espacenet - Bibliographic data|website=worldwide.espacenet.com|access-date=2019-02-28}}{{Cite web|url=https://worldwide.espacenet.com/publicationDetails/biblio?CC=US&NR=2016054293A1&KC=A1&FT=D|title=Espacenet - Bibliographic data|website=worldwide.espacenet.com|access-date=2019-02-28}}{{Cite web|url=https://worldwide.espacenet.com/publicationDetails/biblio?CC=US&NR=2017299607A1&KC=A1&FT=D|title=Espacenet - Bibliographic data|website=worldwide.espacenet.com|access-date=2019-02-28}}{{Cite web|url=https://worldwide.espacenet.com/publicationDetails/biblio?CC=WO&NR=2016063024A1&KC=A1&FT=D|title=Espacenet - Bibliographic data|website=worldwide.espacenet.com|access-date=2019-02-28}} haemoglobinopathies, thalassemia,{{Cite web|url=http://appft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&p=1&u=/netahtml/PTO/srchnum.html&r=1&f=G&l=50&d=PG01&s1=20180224462.PGNR.%5D|title=United States Patent Application: 0190069352|website=appft.uspto.gov|access-date=2019-02-28}} and diabetes,{{cite patent|title=System and method for point to multipoint inter-domain MPLS traffic engineering path calculation|country=US|number=RE47260|issue-date=February 26, 2019|inventor-last=Zhao|inventor2-last=Chen|inventor-first=Qianglin Quintin|inventor2-first=Huaimo}} and two cancer-related patents.{{Cite web|url=https://worldwide.espacenet.com/publicationDetails/biblio?CC=WO&NR=2010052503A1&KC=A1&FT=D|title=Espacenet - Bibliographic data|website=worldwide.espacenet.com|access-date=2019-02-28}}{{Cite web|url=https://worldwide.espacenet.com/publicationDetails/biblio?CC=US&NR=2016115550A1&KC=A1&FT=D%5D|title=Espacenet - Bibliographic data|website=worldwide.espacenet.com|access-date=2019-02-28}}
His academic career, after leaving St Bartholomew's, included being Professor of Biomedical Science at Middlesex University heading a Biomedical Science Research Facility, which incorporated molecular pathology, bio-modelling/bioinformatics and environmental health,{{Cite web|url=http://www.eis.mdx.ac.uk/research/eit/CancerWebPage/welcome.html|title = Middlesex University Centre for Investigative & Diagnostic Oncology}}{{Cite book|url=https://books.google.com/books?id=0vJ5AgAAQBAJ&q=Ray+Iles+Middlesex+University&pg=PR14|title = Reading and Dyslexia in Different Orthographies|isbn = 9781135167813|last1 = Brunswick|first1 = Nicola|last2 = McDougall|first2 = Sine|last3 = Davies|first3 = Paul de Mornay|date = 10 June 2010| publisher=Psychology Press }} and then Anglia Ruskin University.{{Cite book|url=https://books.google.com/books?id=s83QAIRofvgC&q=Ray+Iles+Anglia+Ruskin+University&pg=PT6|title = Biomedical Sciences: Essential Laboratory Medicine|isbn = 9781119962410|last1 = Iles|first1 = Raymond|last2 = Docherty|first2 = Suzanne|date = 29 November 2011| publisher=John Wiley & Sons }}
Formerly a regular contributor to Kumar and Clark's Clinical Medicine,{{Cite web|url=https://worldwide.espacenet.com/publicationDetails/biblio?CC=WO&NR=03065043A2&KC=A2&FT=D%5D|title=Espacenet - Bibliographic data|website=worldwide.espacenet.com|access-date=2019-02-28}} Iles left academia to concentrate on the two organisations that he co-founded, NISAD and MapSciences.
In 2012, with Suzanne Docherty, he published the textbook Biomedical Science: Essential Laboratory Medicine.
NISAD has supported several research projects of Iles and his students in bioanalysis,{{Cite journal|last1=Trivedi|first1=Drupad K.|last2=Iles|first2=Ray K.|date=November 2014|title=Do not just do it, do it right: urinary metabolomics -establishing clinically relevant baselines: Choosing correct tools for shotgun urinary metabolomics|journal=Biomedical Chromatography|language=en|volume=28|issue=11|pages=1491–1501|doi=10.1002/bmc.3219|pmid=24788800}} cancer research,{{Cite journal|last=Iles|first=R.K.|date=January 2007|title=Ectopic hCGβ expression by epithelial cancer: Malignant behaviour, metastasis and inhibition of tumor cell apoptosis|journal=Molecular and Cellular Endocrinology|volume=260-262|pages=264–270|doi=10.1016/j.mce.2006.02.019|pmid=17069968|s2cid=21216536|issn=0303-7207}}{{Cite journal|last1=Butler|first1=Stephen A.|last2=Staite|first2=Edyta M.|last3=Iles|first3=Ray K.|date=2003-01-01|title=Reduction of Bladder Cancer Cell Growth in Response to hCGβ CTP37 Vaccinated Mouse Serum|journal=Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics|volume=14|issue=2|pages=93–100|doi=10.3727/000000003108748649|pmid=14649543|issn=0965-0407}} fertility{{Cite journal|last1=Butler|first1=Stephen A.|last2=Luttoo|first2=Jameel|last3=Freire|first3=Maísa O. T.|last4=Abban|first4=Thomas K.|last5=Borrelli|first5=Paola T. A.|last6=Iles|first6=Ray K.|date=September 2013|title=Human Chorionic Gonadotropin (hCG) in the Secretome of Cultured Embryos: Hyperglycosylated hCG and hCG-Free Beta Subunit Are Potential Markers for Infertility Management and Treatment|journal=Reproductive Sciences|language=en|volume=20|issue=9|pages=1038–1045|doi=10.1177/1933719112472739|pmid=23439616|s2cid=25291112|issn=1933-7191}} and prenatal care and child development.{{Cite journal|last1=Trivedi|first1=Drupad K.|last2=Iles|first2=Ray K.|date=August 2015|title=Shotgun metabolomic profiles in maternal urine identify potential mass spectral markers of abnormal fetal biochemistry - dihydrouracil and progesterone in the metabolism of Down syndrome: Maternal urinary metabolomics markers of Down syndrome|journal=Biomedical Chromatography|language=en|volume=29|issue=8|pages=1173–1183|doi=10.1002/bmc.3404|pmid=25545476}}{{Cite journal|last1=Iles|first1=Ray|last2=Cole|first2=Laurence|last3=Butler|first3=Stephen|date=2014-06-05|title=Direct Analysis of hCGβcf Glycosylation in Normal and Aberrant Pregnancy by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry|journal=International Journal of Molecular Sciences|language=en|volume=15|issue=6|pages=10067–10082|doi=10.3390/ijms150610067|pmid=24905406|issn=1422-0067|pmc=4100140|doi-access=free}}{{Cite journal|last1=Butler|first1=Stephen A.|last2=Abban|first2=Thomas K.A.|last3=Borrelli|first3=Paola T.A.|last4=Luttoo|first4=Jameel M.|last5=Kemp|first5=Bryn|last6=Iles|first6=Ray K.|date=September 2013|title=Single point biochemical measurement algorithm for early diagnosis of ectopic pregnancy|journal=Clinical Biochemistry|language=en|volume=46|issue=13–14|pages=1257–1263|doi=10.1016/j.clinbiochem.2013.06.019|pmid=23830901}}
In 2019 Iles became founding dean at Abu Dhabi University’s College of Health Sciences. In July 2020 he became visiting professor at the Laboratory of Viral Zoonotics, University of Cambridge.{{Cite web |title=Ray Iles |url=https://www.researchgate.net/profile/Ray-Iles |access-date=13 February 2023 |website=ResearchGate}}
Personal life
As a boy Iles attended Mellow Lane Comprehensive School in Hayes, Middlesex.{{cite tweet|number=1279689782705246210|user=Schleswigboy|title= Didn't realise that I was from one of the two first ever Comprehensive schools. Streamed b… |date=5 July 2020}}
His cousin is the UK Olympic fencer Richard Kruse, which was the subject of the BBC Radio programme Tracing your Roots.
References
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Category:British medical researchers
Category:Academics of Middlesex University
Category:Academics of Anglia Ruskin University