Release modulator

A release modulator, or neurotransmitter release modulator, is a type of drug that modulates the release of one or more neurotransmitters. Examples of release modulators include monoamine releasing agents such as the substituted amphetamines (which induce the release of norepinephrine, dopamine, and/or serotonin){{cite journal |last1=Rothman |first1=RB |last2=Baumann |first2=MH |last3=Dersch |first3=CM |last4=Romero |first4=DV |last5=Rice |first5=KC |last6=Carroll |first6=FI |last7=Partilla |first7=JS |title=Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin. |journal=Synapse (New York, N.Y.) |date=January 2001 |volume=39 |issue=1 |pages=32–41 |doi=10.1002/1098-2396(20010101)39:1<32::AID-SYN5>3.0.CO;2-3 |pmid=11071707 |url=https://onlinelibrary.wiley.com/doi/abs/10.1002/1098-2396(20010101)39:1%3C32::AID-SYN5%3E3.0.CO;2-3 |access-date=21 August 2024|url-access=subscription }} and release inhibitors such as botulinum toxin A (which inhibits acetylcholine release by inactivating SNAP-25, thereby preventing exocytosis from occurring).{{cite journal |last1=Montecucco |first1=Cesare |last2=Molgó |first2=Jordi |title=Botulinal neurotoxins: revival of an old killer |journal=Current Opinion in Pharmacology |date=June 2005 |volume=5 |issue=3 |pages=274–279 |doi=10.1016/j.coph.2004.12.006 |pmid=15907915 |access-date=21 August 2024| url = https://pubmed.ncbi.nlm.nih.gov/15907915/}}